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Clopidogrel ratiopharm · 4.5 · 8 As with other oral P2Y12 inhibitors, co-administration of opioid agonists has the potential to delay and red
Eintrag öffnenClopidogrel ratiopharm · 4.5 · A significantly reduced platelet inhibition has been shown in HIV patients treated with ritonavir-or cobicista
Eintrag öffnenClopidogrel ratiopharm · 4.5 · Acetylsalicylic acid (ASA): ASA did not modify the clopidogrel-mediated inhibition of ADP-induced platelet agg
Eintrag öffnenClopidogrel ratiopharm · 4.5 · Apart from the specific medicinal product interaction information described above, interaction studies with cl
Eintrag öffnenClopidogrel ratiopharm · 4.5 · Boosted anti-retroviral therapy (ART): HIV patients treated with boosted anti-retroviral therapies (ART) are a
Eintrag öffnenClopidogrel ratiopharm · 4.5 · CYP2C8 substrate medicinal products: Clopidogrel has been shown to increase repaglinide exposure in healthy vo
Eintrag öffnenClopidogrel ratiopharm · 4.5 · Data from the CAPRIE study indicate that phenytoin and tolbutamide which are metabolised by CYP2C9 can be safe
Eintrag öffnenClopidogrel ratiopharm · 4.5 · Glycoprotein IIb/IIIa inhibitors: clopidogrel should be used with caution in patients who receive concomitant
Eintrag öffnenClopidogrel ratiopharm · 4.5 · Heparin: in a clinical study conducted in healthy subjects, clopidogrel did not necessitate modification of th
Eintrag öffnenClopidogrel ratiopharm · 4.5 · Inducers of CYP2C19 Since clopidogrel is metabolised to its active metabolite partly by CYP2C19, use of medici
Eintrag öffnenClopidogrel ratiopharm · 4.5 · Inhibitors of CYP2C19 Since clopidogrel is metabolised to its active metabolite partly by CYP2C19, use of medi
Eintrag öffnenClopidogrel ratiopharm · 4.5 · Less pronounced reductions of metabolite exposure has been observed with pantoprazole or lansoprazole. The pla
Eintrag öffnenClopidogrel ratiopharm · 4.5 · Medicinal products associated with bleeding risk: There is an increased risk of bleeding due to the potential
Eintrag öffnenClopidogrel ratiopharm · 4.5 · Medicinal products that are strong or moderate CYP2C19 inhibitors include, for example, omeprazole and esomepr
Eintrag öffnenClopidogrel ratiopharm · 4.5 · NSAIDs: in a clinical study conducted in healthy volunteers, the concomitant administration of clopidogrel and
Eintrag öffnenClopidogrel ratiopharm · 4.5 · Oral anticoagulants: the concomitant administration of clopidogrel with oral anticoagulants is not recommended
Eintrag öffnenClopidogrel ratiopharm · 4.5 · Other concomitant therapy:
Eintrag öffnenClopidogrel ratiopharm · 4.5 · Other medicinal products: A number of other clinical studies have been conducted with clopidogrel and other co
Eintrag öffnenClopidogrel ratiopharm · 4.5 · Proton Pump Inhibitors (PPI): Omeprazole 80 mg once daily administered either at the same time as clopidogrel
Eintrag öffnenClopidogrel ratiopharm · 4.5 · Rifampicin strongly induces CYP2C19, resulting in both an increased level of clopidogrel active metabolite and
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