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20 angezeigte Treffer · Seite 2, keine Gesamtzahl für „significant“
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Begriffe & Kennungen
Aptivus · 4.5 · 10 Non-nucleoside reverse transcriptase inhibitors (NNRTIs) Efavirenz 600 mg QD No clinically significant No d
Eintrag öffnenAptivus · 4.5 · Concomitant use of Aptivus/ritonavir caused a decrease of etravirine exposure that could significantly impair
Eintrag öffnenAptivus · 4.5 · No clinically significant change is observed in tipranavir PK parameters. Rifampicin Co-administration of prot
Eintrag öffnenAptivus · 4.8 · Aptivus co-administered with low dose ritonavir, has been associated with reports of significant liver toxicit
Eintrag öffnenAquipta · 4.5 · Strong CYP3A4 inhibitors (e.g., ketoconazole, itraconazole, clarithromycin, ritonavir) can significantly incre
Eintrag öffnenArava · 4.3 · • Patients with significantly impaired bone marrow function or significant anaemia, leucopenia, neutropenia or
Eintrag öffnenArava · 4.3 · • Patients with significantly impaired bone marrow function or significant anaemia, leucopenia, neutropenia or
Eintrag öffnenArava · 4.3 · • Patients with significantly impaired bone marrow function or significant anaemia, leucopenia, neutropenia or
Eintrag öffnenArava · 4.8 · General disorders and administration site conditions Common: anorexia, weight loss (usually insignificant), as
Eintrag öffnenArava · 4.8 · General disorders and administration site conditions Common: anorexia, weight loss (usually insignificant), as
Eintrag öffnenArava · 4.8 · General disorders and administration site conditions Common: anorexia, weight loss (usually insignificant), as
Eintrag öffnenAripiprazole Sandoz · 4.5 · In clinical studies, 10-30 mg/day doses of aripiprazole had no significant effect on the metabolism of substra
Eintrag öffnenAtriance · 4.5 · Nelarabine and ara-G did not significantly inhibit the activities of the major hepatic cytochrome P450 (CYP) i
Eintrag öffnenAubagio · 4.3 · Patients with significantly impaired bone marrow function or significant anaemia, leukopenia, neutropenia or t
Eintrag öffnenAwiqli · 4.8 · The proportion of patients reporting severe or clinically significant hypoglycaemic episodes for insulin icode
Eintrag öffnenAwiqli · 4.8 · The proportion of patients reporting severe or clinically significant hypoglycaemic episodes for insulin icode
Eintrag öffnenAwiqli · 4.8 · The rates of severe or clinically significant hypoglycaemic episodes per PYE for insulin icodec vs daily basal
Eintrag öffnenAzacitidine Mylan · 4.5 · Clinically significant inhibitory or inductive effects of azacitidine on cytochrome P450 enzymes are unlikely
Eintrag öffnenBeromun · 4.3 · Significant cardiovascular disease, e.g. congestive heart failure (New York Heart Association Class II, III or
Eintrag öffnenBeromun · 4.3 · Significant haematological dysfunction, e.g. leucocytes < 2.5 x 109/l, haemoglobin < 9 g/dl, platelets < 60 x
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