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Eintrag öffnenOgsiveo · 4.5 · Effect of acid‑reducing agents Nirogacestat has pH‑dependent solubility, with substantially reduced solubility
Eintrag öffnenPyrukynd · 4.5 · Gastric acid-reducing agents Mitapivat exhibits pH-dependent solubility (see section 5.2) and coadministration
Eintrag öffnenQuviviq · 4.5 · Gastric pH-modifiers The solubility of daridorexant is pH-dependent. In healthy subjects, co-administration wi
Eintrag öffnenRetsevmo · 4.5 · Selpercatinib has pH-dependent solubility, with decreased solubility at higher pH. No clinically significant d
Eintrag öffnenRetsevmo · 4.5 · Selpercatinib has pH-dependent solubility, with decreased solubility at higher pH. No clinically significant d
Eintrag öffnenReyataz · 4.5 · The mechanism of interaction is decreased solubility of atazanavir as intra-gastric pH increases with H2-block
Eintrag öffnenReyataz · 4.5 · The mechanism of interaction is decreased solubility of atazanavir as intra-gastric pH increases with H2-block
Eintrag öffnenSprycel · 4.5 · 47 Antacids Non-clinical data demonstrate that the solubility of dasatinib is pH-dependent. In healthy subject
Eintrag öffnenSprycel · 4.5 · Antacids Non-clinical data demonstrate that the solubility of dasatinib is pH-dependent. In healthy subjects,
Eintrag öffnenTarceva · 4.5 · Erlotinib and medicinal products altering pH Erlotinib is characterised by a decrease in solubility at pH abov
Eintrag öffnenTasigna · 4.5 · Nilotinib has pH dependent solubility, with lower solubility at higher pH. In healthy subjects receiving esome
Eintrag öffnenTyverb · 4.5 · The solubility of lapatinib is pH-dependent. Concomitant treatment with substances that increase gastric pH sh
Eintrag öffnenVizimpro · 4.5 · The aqueous solubility of dacomitinib is pH dependent, with low (acidic) pH resulting in higher solubility. Da
Eintrag öffnenVosevi · 4.5 · (Increase in gastric pH decreases velpatasvir solubility)
Eintrag öffnenVosevi · 4.5 · (Increase in gastric pH decreases velpatasvir solubility) ANTIARRHYTHMICS Amiodarone Effect on amiodarone, vox
Eintrag öffnenVosevi · 4.5 · (Increase in gastric pH decreases velpatasvir solubility) Omeprazole Observed: (20 mg once daily) + Sofosbuvir
Eintrag öffnenWayrilz · 4.5 · Rilzabrutinib solubility decreases with increasing pH. Co-administration with a PPI (esomeprazole) decreased r
Eintrag öffnenXalkori · 4.5 · Coadministration with medicinal products that increase gastric pH The aqueous solubility of crizotinib is pH d
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