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Alecensa · 4.5 · CYP substrates In vitro, alectinib and M4 show weak time-dependent inhibition of CYP3A4, and alectinib exhibit
Eintrag öffnenAlecensa · 4.5 · P-gp substrates In vitro, alectinib and its major active metabolite M4 are inhibitors of the efflux transporte
Eintrag öffnenAnoro Ellipta (previously Anoro) · 4.5 · Both umeclidinium and vilanterol are substrates of the P-glycoprotein transporter (P-gp). The effect of the mo
Eintrag öffnenArava · 4.5 · Effect on organic anion transporter 3 (OAT3) substrates There was an increase in mean cefaclor Cmax and AUC (1
Eintrag öffnenArava · 4.5 · Effect on organic anion transporter 3 (OAT3) substrates There was an increase in mean cefaclor Cmax and AUC (1
Eintrag öffnenArava · 4.5 · Effect on organic anion transporter 3 (OAT3) substrates There was an increase in mean cefaclor Cmax and AUC (1
Eintrag öffnenAubagio · 4.5 · Effect of teriflunomide on organic anion transporter 3 (OAT3) substrates There was an increase in mean cefaclo
Eintrag öffnenBalversa · 4.5 · Major CYP isoform substrates (including hormonal contraceptives) Mean ratios of Cmax and AUC∞ for midazolam (a
Eintrag öffnenBalversa · 4.5 · Organic cation transporter 2 (OCT2) substrates Mean ratios of Cmax and AUC∞ for metformin (a sensitive OCT2 su
Eintrag öffnenBalversa · 4.5 · P-Glycoprotein (P-gp) substrates Erdafitinib is an inhibitor of P-gp. Concomitant administration of Balversa w
Eintrag öffnenBesponsa · 4.5 · 8 to alter the exposure of substrates of CYP enzymes, and N-acetyl-gamma-calicheamicin dimethylhydrazide is un
Eintrag öffnenBesremi · 4.5 · Therefore, care should be taken when ropeginterferon alfa-2b is co- substrates notably those having a narrow t
Eintrag öffnenBetmiga · 4.5 · Effect of mirabegron on CYP2D6 substrates In healthy volunteers, the inhibitory potency of mirabegron towards
Eintrag öffnenBetmiga · 4.5 · Effect of mirabegron on CYP2D6 substrates In healthy volunteers, the inhibitory potency of mirabegron towards
Eintrag öffnenBraftovi · 4.5 · CYP substrates Encorafenib is a strong inducer of CYP3A4. Concomitant use with agents that are substrates of C
Eintrag öffnenBraftovi · 4.5 · Transporter substrates In vivo, encorafenib is an inhibitor of OATP1B1, OATP1B3 and/or BCRP. Coadministration
Eintrag öffnenBrilique · 4.5 · P-gp substrates (including digoxin, cyclosporine) Concomitant administration of ticagrelor increased the digox
Eintrag öffnenBrilique · 4.5 · P-gp substrates (including digoxin, cyclosporine) Concomitant administration of ticagrelor increased the digox
Eintrag öffnenBrilique · 4.5 · P-gp substrates (including digoxin, cyclosporine) Concomitant administration of ticagrelor increased the digox
Eintrag öffnenBrilique · 4.5 · There was no effect of ticagrelor on cyclosporine blood levels. Effect of ticagrelor on other P-gp substrates
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