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Emend · 4.5 · Immunosuppressants During the 3-day CINV regimen, a transient moderate increase followed by a mild decrease in
Eintrag öffnenEmend · 4.5 · Immunosuppressants During the 3-day CINV regimen, a transient moderate increase followed by a mild decrease in
Eintrag öffnenEmend · 4.5 · In a clinical study, single doses of an oral contraceptive containing ethinyl estradiol and norethindrone were
Eintrag öffnenEmend · 4.5 · In a clinical study, single doses of an oral contraceptive containing ethinyl estradiol and norethindrone were
Eintrag öffnenEmend · 4.5 · In a third study with intravenous and oral administration of midazolam, EMEND was given as 125 mg on Day 1 and
Eintrag öffnenEmend · 4.5 · In a third study with intravenous and oral administration of midazolam, EMEND was given as 125 mg on Day 1 and
Eintrag öffnenEmend · 4.5 · In another study with intravenous administration of midazolam, EMEND was given as 125 mg on Day 1 and 80 mg/da
Eintrag öffnenEmend · 4.5 · In another study with intravenous administration of midazolam, EMEND was given as 125 mg on Day 1 and 80 mg/da
Eintrag öffnenEmend · 4.5 · Induction As a mild inducer of CYP2C9, CYP3A4 and glucuronidation, aprepitant can decrease plasma concentratio
Eintrag öffnenEmend · 4.5 · Induction As a mild inducer of CYP2C9, CYP3A4 and glucuronidation, aprepitant can decrease plasma concentratio
Eintrag öffnenEmend · 4.5 · Ketoconazole When a single 125 mg dose of aprepitant was administered on Day 5 of a 10-day regimen of 400 mg/d
Eintrag öffnenEmend · 4.5 · Ketoconazole When a single 125 mg dose of aprepitant was administered on Day 5 of a 10-day regimen of 400 mg/d
Eintrag öffnenEmend · 4.5 · Methylprednisolone: The usual intravenously administered methylprednisolone dose should be reduced approximate
Eintrag öffnenEmend · 4.5 · Methylprednisolone: The usual intravenously administered methylprednisolone dose should be reduced approximate
Eintrag öffnenEmend · 4.5 · Midazolam The potential effects of increased plasma concentrations of midazolam or other benzodiazepines metab
Eintrag öffnenEmend · 4.5 · Paediatric population Interaction studies have only been performed in adults.
Eintrag öffnenEmend · 4.5 · Paediatric population Interaction studies have only been performed in adults.
Eintrag öffnenEmend · 4.5 · Rifampicin When a single 375 mg dose of aprepitant was administered on Day 9 of a 14-day regimen of 600 mg/day
Eintrag öffnenEmend · 4.5 · Rifampicin When a single 375 mg dose of aprepitant was administered on Day 9 of a 14-day regimen of 600 mg/day
Eintrag öffnenEmend · 4.5 · Tolbutamide EMEND, when given as 125 mg on Day 1 and 80 mg/day on Days 2 and 3, decreased the AUC of tolbutami
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