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Neparvis · 4.5 · OATP1B1 and OATP1B3 substrates, e.g. statins In vitro data indicate that sacubitril inhibits OATP1B1 and OATP1
Eintrag öffnenNeparvis · 4.5 · PDE5 inhibitors including sildenafil Addition of a single dose of sildenafil to sacubitril/valsartan at steady
Eintrag öffnenNeparvis · 4.5 · PDE5 inhibitors including sildenafil Addition of a single dose of sildenafil to sacubitril/valsartan at steady
Eintrag öffnenNeparvis · 4.5 · Potassium Concomitant use of potassium-sparing diuretics (triamterene, amiloride), mineralocorticoid antagonis
Eintrag öffnenNeparvis · 4.5 · Potassium Concomitant use of potassium-sparing diuretics (triamterene, amiloride), mineralocorticoid antagonis
Eintrag öffnenNeparvis · 4.5 · Sacubitril/valsartan contains valsartan, and therefore should not be co-administered with another ARB containi
Eintrag öffnenNeparvis · 4.5 · Sacubitril/valsartan contains valsartan, and therefore should not be co-administered with another ARB containi
Eintrag öffnenNeparvis · 4.6 Fertility, pregnancy and lactation · 1
Eintrag öffnenNeparvis · 4.6 Fertility, pregnancy and lactation · 2
Eintrag öffnenNeparvis · 4.8 Undesirable effects · 1
Eintrag öffnenNeparvis · 4.8 Undesirable effects · 2
Eintrag öffnenNeparvis · 4.8 · 10 Table 2 List of adverse reactions
Eintrag öffnenNeparvis · 4.8 · 11 Renal impairment In PARADIGM-HF, renal impairment was reported in 10.1% of sacubitril/valsartan-treated pat
Eintrag öffnenNeparvis · 4.8 · 30 Description of selected adverse reactions
Eintrag öffnenNeparvis · 4.8 · Adverse reactions are ranked by System organ class and then by frequency with the most frequent first, using t
Eintrag öffnenNeparvis · 4.8 · Adverse reactions are ranked by System organ class and then by frequency with the most frequent first, using t
Eintrag öffnenNeparvis · 4.8 · Angioedema Angioedema has been reported in patients treated with sacubitril/valsartan. In PARADIGM-HF, angioed
Eintrag öffnenNeparvis · 4.8 · Angioedema Angioedema has been reported in patients treated with sacubitril/valsartan. In PARADIGM-HF, angioed
Eintrag öffnenNeparvis · 4.8 · Blood pressure In PARADIGM-HF, hypotension and clinically relevant low systolic blood pressure (<90 mmHg and d
Eintrag öffnenNeparvis · 4.8 · Blood pressure In PARADIGM-HF, hypotension and clinically relevant low systolic blood pressure (<90 mmHg and d
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