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20 angezeigte Treffer · Seite 3, keine Gesamtzahl für „Orgovyx“
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Begriffe & Kennungen
Orgovyx · 4.5 · In vitro studies Cytochrome P450 (CYP) enzymes: Relugolix is not an inhibitor of CYP1A2, CYP2B6, CYP2C8, CYP2C
Eintrag öffnenOrgovyx · 4.5 · Interacting drug dose Relugolix Change in Change in Recommendation regimen dose relugolix relugolix regimen AU
Eintrag öffnenOrgovyx · 4.5 · Medicinal herb St. John’s Wort (Hypericum perforatum).
Eintrag öffnenOrgovyx · 4.5 · Medicinal products Therapeutic Expected: ↓ Expected: ↓ that are combined P dose for gp and strong Orgovyx CYP3
Eintrag öffnenOrgovyx · 4.5 · Medicinal products that are BCRP substrates
Eintrag öffnenOrgovyx · 4.5 · Medicinal products that are CYP3A substrates
Eintrag öffnenOrgovyx · 4.5 · Medicinal products that are CYP3A4 inhibitors voriconazole 120 mg 12% ↑ 18% ↓ No dose single dose modification
Eintrag öffnenOrgovyx · 4.5 · Medicinal products that are combined P gp and strong CYP3A4 inducers
Eintrag öffnenOrgovyx · 4.5 · Medicinal products that are oral P gp inhibitors erythromycin 120 mg 3.5 -fold ↑ 2.9 -fold ↑ Concomitant use o
Eintrag öffnenOrgovyx · 4.5 · No clinically significant differences in the pharmacokinetics of relugolix were observed upon co-administratio
Eintrag öffnenOrgovyx · 4.5 · No dose adjustment of Orgovyx is required.
Eintrag öffnenOrgovyx · 4.5 · Non nucleoside reverse transcriptase inhibitors efavirenz. Combination with other medicines for advanced hormo
Eintrag öffnenOrgovyx · 4.5 · Other medicinal Therapeutic Expected: ↑ Expected: ↑ products that are P-gp dose for inhibitor include (but Org
Eintrag öffnenOrgovyx · 4.5 · Other medicinal products
Eintrag öffnenOrgovyx · 4.5 · P-gp inhibitors
Eintrag öffnenOrgovyx · 4.5 · Potential for other medicinal products to affect the exposure to relugolix
Eintrag öffnenOrgovyx · 4.5 · Relugolix is a weak inducer of CYP3A mediated metabolism, and an inhibitor of BCRP and P-gp in vitro. Effect o
Eintrag öffnenOrgovyx · 4.5 · Since androgen deprivation treatment may prolong the QT interval, the concomitant use of Orgovyx with medicina
Eintrag öffnenOrgovyx · 4.5 · Table 2. Effect of relugolix on exposure (Cmax, AUC0-inf) of co-administered medicinal products and recommenda
Eintrag öffnenOrgovyx · 4.5 · Therapeutic dose for Apalutamide Expected: Expected: Orgovyx ↔ ↔ (CYP2C8 and CYP3A4 substrate)
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