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Levodopa/Carbidopa/Entacapone Orion · 4.3 Contraindications · 1
Eintrag öffnenLevodopa/Carbidopa/Entacapone Orion · 4.3 · - Hypersensitivity to the active substances or to any of the excipients listed in section 6.1. - Severe hepati
Eintrag öffnenLevodopa/Carbidopa/Entacapone Orion · 4.4 Special warnings and precautions for use · 1
Eintrag öffnenLevodopa/Carbidopa/Entacapone Orion · 4.5 Interaction with other medicinal products and other forms of interaction · 1
Eintrag öffnenLevodopa/Carbidopa/Entacapone Orion · 4.5 · 7 [CI90 6–19%]. Thus, a control of INR is recommended when Levodopa/Carbidopa/Entacapone Orion is initiated fo
Eintrag öffnenLevodopa/Carbidopa/Entacapone Orion · 4.5 · Antidepressants: Rarely, reactions including hypertension and dyskinesia have been reported with the concomita
Eintrag öffnenLevodopa/Carbidopa/Entacapone Orion · 4.5 · Antihypertensives: Symptomatic postural hypotension may occur when levodopa is added to the treatment of patie
Eintrag öffnenLevodopa/Carbidopa/Entacapone Orion · 4.5 · Caution should be exercised when the following active substances are administered concomitantly with levodopa
Eintrag öffnenLevodopa/Carbidopa/Entacapone Orion · 4.5 · Due to entacapone's affinity to cytochrome P450 2C9 in vitro (see section 5.2), Levodopa/Carbidopa/Entacapone
Eintrag öffnenLevodopa/Carbidopa/Entacapone Orion · 4.5 · In vitro data: Entacapone binds to human albumin binding site II which also binds several other medicinal prod
Eintrag öffnenLevodopa/Carbidopa/Entacapone Orion · 4.5 · Levodopa and entacapone may form chelates with iron in the gastrointestinal tract. Therefore, Levodopa/Carbido
Eintrag öffnenLevodopa/Carbidopa/Entacapone Orion · 4.5 · Other active substances: Dopamine receptor antagonists (e.g. some antipsychotics and antiemetics), phenytoin a
Eintrag öffnenLevodopa/Carbidopa/Entacapone Orion · 4.5 · Other antiparkinsonian medicinal products: To date there has been no indication of interactions that would pre
Eintrag öffnenLevodopa/Carbidopa/Entacapone Orion · 4.5 · Other forms of interactions: Since levodopa competes with certain amino acids, the absorption of Levodopa/Carb
Eintrag öffnenLevodopa/Carbidopa/Entacapone Orion · 4.6 Fertility, pregnancy and lactation · 1
Eintrag öffnenLevodopa/Carbidopa/Entacapone Orion · 4.8 Undesirable effects · 1
Eintrag öffnenLevodopa/Carbidopa/Entacapone Orion · 4.8 · **The incidence rates of myocardial infarction and other ischemic heart disease events (0.43% and 1.54%, respe
Eintrag öffnenLevodopa/Carbidopa/Entacapone Orion · 4.8 · *Adverse reactions that are mainly attributable to entacapone or are more frequent (by the frequency differenc
Eintrag öffnenLevodopa/Carbidopa/Entacapone Orion · 4.8 · 10 Dopamine Dysregulation Syndrome (DDS) is an addictive disorder seen in some patients treated with carbidopa
Eintrag öffnenLevodopa/Carbidopa/Entacapone Orion · 4.8 · 8 identified from the clinical trials with Levodopa/Carbidopa/Entacapone Orion or entacapone combined with lev
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