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Osenvelt · 4.8 · Overall safety profile is consistent in all approved indications for denosumab.
Eintrag öffnenOsenvelt · 4.8 · Paediatric population
Eintrag öffnenOsenvelt · 4.8 · Renal impairment In a clinical study of patients without advanced cancer with severe renal impairment (creatin
Eintrag öffnenOsenvelt · 4.8 · Reporting of suspected adverse reactions
Eintrag öffnenOsenvelt · 4.8 · Reporting suspected adverse reactions after authorisation of the medicinal product is important. It allows con
Eintrag öffnenOsenvelt · 4.8 · Study 7 was conducted to continue to follow subjects with GCTB who were treated in study 6 for an additional 5
Eintrag öffnenOsenvelt · 4.8 · Summary of the safety profile
Eintrag öffnenOsenvelt · 4.8 · Table 1. Adverse reactions reported in patients with advanced malignancies involving bone, multiple myeloma, o
Eintrag öffnenOsenvelt · 4.8 · Tabulated list of adverse reactions
Eintrag öffnenOsenvelt · 4.8 · The cumulative incidence at one year was 1.1% for denosumab and 0.6 % for zoledronic acid, respectively.
Eintrag öffnenOsenvelt · 4.8 · The following convention has been used for the classification of the adverse reactions based on incidence rate
Eintrag öffnenOsenvelt · 4.8 · The highest incidence of hypocalcaemia was observed in a phase III trial in patients with multiple myeloma. Hy
Eintrag öffnenOsenvelt · 4.8 · The patient-year adjusted overall incidence of confirmed ONJ was 1.1 per 100 patient-years during the first ye
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