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Alymsys · 4.8 · Bevacizumab use has been associated with serious cases of fistulae including reactions resulting in death.
Eintrag öffnenAlymsys · 4.8 · In NSABP C-08, a phase III trial of bevacizumab in adjuvant treatment of patients with colon cancer, the incid
Eintrag öffnenAlymsys · 4.8 · In bevacizumab clinical trials, gastrointestinal fistulae (all grade) have been reported with an incidence of
Eintrag öffnenAlymsys · 4.8 · In clinical trials with bevacizumab, congestive heart failure (CHF) was observed in all cancer indications stu
Eintrag öffnenAlymsys · 4.8 · In most clinical trials of bevacizumab, patients with pre-existing CHF of NYHA (New York Heart Association) II
Eintrag öffnenAlymsys · 4.8 · In one clinical trial evaluating bevacizumab in combination with 5-fluorouracil/folinic acid, AVF2192g, patien
Eintrag öffnenAlymsys · 4.8 · In study BO20924 of bevacizumab with current standard of care in rhabdomyosarcoma and non-rhabdomyosarcoma sof
Eintrag öffnenAlymsys · 4.8 · In study BO25041 of bevacizumab added to post-operative radiation therapy (RT) with concomitant and adjuvant t
Eintrag öffnenAlymsys · 4.8 · In study JO25567, all grade hypertension was observed in 77.3% of the patients who received bevacizumab in com
Eintrag öffnenAlymsys · 4.8 · Some of the adverse reactions are reactions commonly seen with chemotherapy; however, bevacizumab may exacerba
Eintrag öffnenAlymsys · 4.8 · Tables 1 and 2 list adverse reactions associated with the use of bevacizumab in combination with different che
Eintrag öffnenAlymsys · 4.8 · The incidence of CNS bleeding in patients with untreated CNS metastases receiving bevacizumab has not been pro
Eintrag öffnenAlymsys · 4.8 · The most frequently observed adverse reactions across clinical trials in patients receiving bevacizumab were h
Eintrag öffnenAlymsys · 4.8 · The overall safety profile of bevacizumab is based on data from over 5,700 patients with various malignancies,
Eintrag öffnenAlymsys · 4.8 · The risk of bevacizumab-associated hypertension did not correlate with the patients’ baseline characteristics,
Eintrag öffnenAlymsys · 4.8 · The safety and efficacy of bevacizumab in children less than 18 years old have not been established.
Eintrag öffnenAlymsys · 4.8 · There have been rare reports of bevacizumab-treated patients developing signs and symptoms that are consistent
Eintrag öffnenAvastin · 4.5 · Combination of bevacizumab and sunitinib malate In two clinical trials of metastatic renal cell carcinoma, mic
Eintrag öffnenAvastin · 4.5 · EGFR monoclonal antibodies in combination with bevacizumab chemotherapy regimens No interaction studies have b
Eintrag öffnenAvastin · 4.5 · Effect of antineoplastic agents on bevacizumab pharmacokinetics No clinically relevant interaction of co-admin
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