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20 angezeigte Treffer · Seite 3, keine Gesamtzahl für „bosentan“
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Tracleer · 4.5 · Bosentan is metabolised by CYP2C9 and CYP3A4. Inhibition of these isoenzymes may increase the plasma concentra
Eintrag öffnenTracleer · 4.5 · Digoxin: Co-administration for 7 days of bosentan 500 mg twice daily with digoxin decreased the AUC, Cmax and
Eintrag öffnenTracleer · 4.5 · Digoxin: Co-administration for 7 days of bosentan 500 mg twice daily with digoxin decreased the AUC, Cmax and
Eintrag öffnenTracleer · 4.5 · Glibenclamide: Co-administration of bosentan 125 mg twice daily for 5 days decreased the plasma concentrations
Eintrag öffnenTracleer · 4.5 · Glibenclamide: Co-administration of bosentan 125 mg twice daily for 5 days decreased the plasma concentrations
Eintrag öffnenTracleer · 4.5 · Hormonal contraceptives: Co-administration of bosentan 125 mg twice daily for 7 days with a single dose of ora
Eintrag öffnenTracleer · 4.5 · Hormonal contraceptives: Co-administration of bosentan 125 mg twice daily for 7 days with a single dose of ora
Eintrag öffnenTracleer · 4.5 · Ketoconazole: Co-administration for 6 days of bosentan 62.5 mg twice daily with ketoconazole, a potent CYP3A4
Eintrag öffnenTracleer · 4.5 · Ketoconazole: Co-administration for 6 days of bosentan 62.5 mg twice daily with ketoconazole, a potent CYP3A4
Eintrag öffnenTracleer · 4.5 · Lopinavir+ritonavir (and other ritonavir-boosted protease inhibitors): Co-administration of bosentan 125 mg tw
Eintrag öffnenTracleer · 4.5 · Rifampicin: Co-administration in 9 healthy subjects for 7 days of bosentan 125 mg twice daily with rifampicin,
Eintrag öffnenTracleer · 4.5 · Rifampicin: Co-administration in 9 healthy subjects for 7 days of bosentan 125 mg twice daily with rifampicin,
Eintrag öffnenTracleer · 4.5 · Sildenafil: Co-administration of bosentan 125 mg twice daily (steady state) with sildenafil 80 mg three times
Eintrag öffnenTracleer · 4.5 · Sildenafil: Co-administration of bosentan 125 mg twice daily (steady state) with sildenafil 80 mg three times
Eintrag öffnenTracleer · 4.5 · Simvastatin: Co-administration of bosentan 125 mg twice daily for 5 days decreased the plasma concentrations o
Eintrag öffnenTracleer · 4.5 · Simvastatin: Co-administration of bosentan 125 mg twice daily for 5 days decreased the plasma concentrations o
Eintrag öffnenTracleer · 4.5 · Tadalafil: Bosentan (125 mg twice daily) reduced tadalafil (40 mg once per day) systemic exposure by 42% and C
Eintrag öffnenTracleer · 4.5 · Tadalafil: Bosentan (125 mg twice daily) reduced tadalafil (40 mg once per day) systemic exposure by 42% and C
Eintrag öffnenTracleer · 4.5 · Warfarin: Co-administration of bosentan 500 mg twice daily for 6 days decreased the plasma concentrations of b
Eintrag öffnenTracleer · 4.5 · Warfarin: Co-administration of bosentan 500 mg twice daily for 6 days decreased the plasma concentrations of b
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