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Aptivus · 4.5 · Metabolic profile of tipranavir Tipranavir is a substrate, an inducer and an inhibitor of cytochrome P450 CYP3
Eintrag öffnenArava · 4.5 · Effect on caffeine (CYP1A2 substrate) Repeated doses of A771726 decreased mean Cmax and AUC of caffeine (CYP1A
Eintrag öffnenArava · 4.5 · Effect on caffeine (CYP1A2 substrate) Repeated doses of A771726 decreased mean Cmax and AUC of caffeine (CYP1A
Eintrag öffnenArava · 4.5 · Effect on caffeine (CYP1A2 substrate) Repeated doses of A771726 decreased mean Cmax and AUC of caffeine (CYP1A
Eintrag öffnenArava · 4.5 · Effect on organic anion transporter 3 (OAT3) substrates There was an increase in mean cefaclor Cmax and AUC (1
Eintrag öffnenArava · 4.5 · Effect on organic anion transporter 3 (OAT3) substrates There was an increase in mean cefaclor Cmax and AUC (1
Eintrag öffnenArava · 4.5 · Effect on organic anion transporter 3 (OAT3) substrates There was an increase in mean cefaclor Cmax and AUC (1
Eintrag öffnenArava · 4.5 · Effect on repaglinide (CYP2C8 substrate) There was an increase in mean repaglinide Cmax and AUC (1.7- and 2.4-
Eintrag öffnenArava · 4.5 · Effect on repaglinide (CYP2C8 substrate) There was an increase in mean repaglinide Cmax and AUC (1.7- and 2.4-
Eintrag öffnenArava · 4.5 · Effect on repaglinide (CYP2C8 substrate) There was an increase in mean repaglinide Cmax and AUC (1.7- and 2.4-
Eintrag öffnenArava · 4.5 · Effect on warfarin (CYP2C9 substrate) Repeated doses of A771726 had no effect on the pharmacokinetics of S-war
Eintrag öffnenArava · 4.5 · Effect on warfarin (CYP2C9 substrate) Repeated doses of A771726 had no effect on the pharmacokinetics of S-war
Eintrag öffnenArava · 4.5 · Effect on warfarin (CYP2C9 substrate) Repeated doses of A771726 had no effect on the pharmacokinetics of S-war
Eintrag öffnenAubagio · 4.5 · Effect of teriflunomide on CYP1A2 substrate: caffeine Repeated doses of teriflunomide decreased mean Cmax and
Eintrag öffnenAubagio · 4.5 · Effect of teriflunomide on CYP2C8 substrate: repaglinide There was an increase in mean repaglinide Cmax and AU
Eintrag öffnenAubagio · 4.5 · Effect of teriflunomide on organic anion transporter 3 (OAT3) substrates There was an increase in mean cefaclo
Eintrag öffnenBalversa · 4.5 · Major CYP isoform substrates (including hormonal contraceptives) Mean ratios of Cmax and AUC∞ for midazolam (a
Eintrag öffnenBalversa · 4.5 · Organic cation transporter 2 (OCT2) substrates Mean ratios of Cmax and AUC∞ for metformin (a sensitive OCT2 su
Eintrag öffnenBalversa · 4.5 · P-Glycoprotein (P-gp) substrates Erdafitinib is an inhibitor of P-gp. Concomitant administration of Balversa w
Eintrag öffnenBaraclude · 4.5 · Entecavir is not a substrate, an inducer or an inhibitor of cytochrome P450 (CYP450) enzymes (see section 5.2)
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