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Invokana · 4.8 · In the pooled analysis of the four 26-week, placebo-controlled studies in adults, the incidence of all adverse
Eintrag öffnenInvokana · 4.8 · Lower limb amputation
Eintrag öffnenInvokana · 4.8 · Lower limb infections, diabetic foot ulcers, peripheral arterial disease, and gangrene, were the most common m
Eintrag öffnenInvokana · 4.8 · Of the subjects, within the CANVAS Program, who had an amputation, the toe and midfoot were the most frequent
Eintrag öffnenInvokana · 4.8 · Paediatric population In Study DIA3018, 171 children aged 10 years and older with type 2 diabetes mellitus rec
Eintrag öffnenInvokana · 4.8 · Patients treated with canagliflozin regardless of baseline eGFR experienced an initial fall in mean eGFR. Ther
Eintrag öffnenInvokana · 4.8 · Renal impairment in adult patients with diabetic kidney disease in type 2 diabetes mellitus In a long-term ren
Eintrag öffnenInvokana · 4.8 · Renal impairment in adult patients with insufficiently controlled type 2 diabetes mellitus Adult patients with
Eintrag öffnenInvokana · 4.8 · Reporting of suspected adverse reactions
Eintrag öffnenInvokana · 4.8 · Reporting suspected adverse reactions after authorisation of the medicinal product is important. It allows con
Eintrag öffnenInvokana · 4.8 · Special populations
Eintrag öffnenInvokana · 4.8 · Summary of the safety profile
Eintrag öffnenInvokana · 4.8 · Table 2: Tabulated list of adverse reactions (MedDRA) from placebo-e and active-controlled studiese and from p
Eintrag öffnenInvokana · 4.8 · Table 3: Integrated analysis of amputations in CANVAS AND CANVAS-R Placebo canagliflozin N = 4344 N = 5790 Tot
Eintrag öffnenInvokana · 4.8 · Tabulated list of adverse reactions
Eintrag öffnenInvokana · 4.8 · The frequency of hypoglycaemia was low (approximately 4%) among treatment groups, including placebo, when used
Eintrag öffnenInvokana · 4.8 · The incidence rates for larger decreases in eGFR (> 30%) at any time during treatment were 7.3, 8.1, and 6.5 e
Eintrag öffnenInvokana · 4.8 · The overall incidence rate of elevated serum potassium was higher in patients with moderate renal impairment w
Eintrag öffnenInvokana · 4.8 · The primary assessment of safety and tolerability was conducted in a pooled analysis (n = 2,313) of four 26-we
Eintrag öffnenInvokana · 4.8 · The safety of canagliflozin was evaluated in 22,645 adult patients with type 2 diabetes, including 13,278 pati
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