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Mekinist · 4.8 · Rhabdomyolysis has been reported in patients taking trametinib alone or in combination with dabrafenib. Signs
Eintrag öffnenMekinist · 4.8 · Summary of the safety profile
Eintrag öffnenMekinist · 4.8 · System organ class Frequency (all Adverse reactions grades) Folliculitis Paronychia Infections and infestation
Eintrag öffnenMekinist · 4.8 · System organ class Frequency (all Adverse reactions grades) Nasopharyngitis Very common Urinary tract infectio
Eintrag öffnenMekinist · 4.8 · Table 4 Adverse reactions with trametinib monotherapy
Eintrag öffnenMekinist · 4.8 · Tabulated list of adverse reactions
Eintrag öffnenMekinist · 4.8 · The most common adverse reactions (incidence ≥20%) for trametinib in combination with dabrafenib were: pyrexia
Eintrag öffnenMekinist · 4.8 · The risk of haemorrhage may be increased with concomitant use of antiplatelet or anticoagulant therapy. If hae
Eintrag öffnenMekinist · 4.8 · The safety and efficacy of the combination of trametinib and dabrafenib have been evaluated in a multi-cohort,
Eintrag öffnenMekinist · 4.8 · The safety of trametinib film-coated tablets has not been evaluated in prospective clinical studies of adolesc
Eintrag öffnenMekinist · 4.8 · The safety of trametinib monotherapy has been evaluated in the integrated safety population of 329 patients wi
Eintrag öffnenMekinist · 4.8 · Trametinib has been reported to decrease LVEF when used as monotherapy or in combination with dabrafenib. In c
Eintrag öffnenMekinist · 4.8 · Trametinib in combination with dabrafenib in patients with brain metastases
Eintrag öffnenMekinist · 4.8 · Visual impairment
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