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Rapamune · 4.5 · Sirolimus is extensively metabolised by the CYP3A4 isozyme in the intestinal wall and liver. Sirolimus is also
Eintrag öffnenRapamune · 4.5 · The rate and extent of sirolimus absorption was significantly increased by ciclosporin A (CsA). Sirolimus admi
Eintrag öffnenRapamune · 4.5 · The rate and extent of sirolimus absorption was significantly increased by ciclosporin A (CsA). Sirolimus admi
Eintrag öffnenRapamune · 4.5 · The simultaneous oral administration of 10 mg of Rapamune oral solution and 120 mg of diltiazem significantly
Eintrag öffnenRapamune · 4.5 · The simultaneous oral administration of 10 mg of Rapamune oral solution and 120 mg of diltiazem significantly
Eintrag öffnenRapamune · 4.5 · There have been reports of increased blood levels of sirolimus during concomitant use with cannabidiol. Co-adm
Eintrag öffnenRapamune · 4.5 · There have been reports of increased blood levels of sirolimus during concomitant use with cannabidiol. Co-adm
Eintrag öffnenRapamune · 4.5 · Verapamil (CYP3A4 inhibitor)
Eintrag öffnenRapamune · 4.5 · Verapamil (CYP3A4 inhibitor)
Eintrag öffnenRapamune · 4.5 · Voriconazole (CYP3A4 inhibitor)
Eintrag öffnenRapamune · 4.6 Fertility, pregnancy and lactation · 1
Eintrag öffnenRapamune · 4.6 Fertility, pregnancy and lactation · 2
Eintrag öffnenRapamune · 4.8 Undesirable effects · 1
Eintrag öffnenRapamune · 4.8 Undesirable effects · 2
Eintrag öffnenRapamune · 4.8 · 11 System organ Very common Common Uncommon Rare Frequency class (≥1/10) (≥1/100 to (≥1/1,000 to (≥1/10,000 no
Eintrag öffnenRapamune · 4.8 · 12 System organ Very common Common Uncommon Rare Frequency class (≥1/10) (≥1/100 to (≥1/1,000 to (≥1/10,000 no
Eintrag öffnenRapamune · 4.8 · 13 Description of selected adverse reactions
Eintrag öffnenRapamune · 4.8 · 14 regimen studied (continuous use of Rapamune in combination with calcineurin inhibitor) is not indicated for
Eintrag öffnenRapamune · 4.8 · 31 Most patients were on immunosuppressive regimens, which included Rapamune in combination with other immunos
Eintrag öffnenRapamune · 4.8 · 32 System organ Very common Common Uncommon Rare Frequency class (≥1/10) (≥1/100 to (≥1/1,000 to (≥1/10,000 no
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