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Spedra · 4.5 · Although specific interactions have not been studied, other CYP3A4 inhibitors, including grapefruit juice woul
Eintrag öffnenSpedra · 4.5 · Antihypertensives other than alpha-blockers A clinical study was conducted to assess the effect of avanafil on
Eintrag öffnenSpedra · 4.5 · Antihypertensives other than alpha-blockers A clinical study was conducted to assess the effect of avanafil on
Eintrag öffnenSpedra · 4.5 · Antihypertensives other than alpha-blockers A clinical study was conducted to assess the effect of avanafil on
Eintrag öffnenSpedra · 4.5 · Based on in vitro data, at clinically relevant concentrations avanafil could be an inhibitor of BCRP. At clini
Eintrag öffnenSpedra · 4.5 · Based on in vitro data, at clinically relevant concentrations avanafil could be an inhibitor of BCRP. At clini
Eintrag öffnenSpedra · 4.5 · Based on in vitro data, at clinically relevant concentrations avanafil could be an inhibitor of BCRP. At clini
Eintrag öffnenSpedra · 4.5 · CYP3A4 Inhibitors Ketoconazole (400 mg daily), a selective and highly potent inhibitor of CYP3A4, increased av
Eintrag öffnenSpedra · 4.5 · CYP3A4 Inhibitors Ketoconazole (400 mg daily), a selective and highly potent inhibitor of CYP3A4, increased av
Eintrag öffnenSpedra · 4.5 · CYP3A4 Inhibitors Ketoconazole (400 mg daily), a selective and highly potent inhibitor of CYP3A4, increased av
Eintrag öffnenSpedra · 4.5 · CYP3A4 substrate Amlodipine (5 mg daily) increased avanafil 200 mg single-dose Cmax and AUC by approximately 2
Eintrag öffnenSpedra · 4.5 · CYP3A4 substrate Amlodipine (5 mg daily) increased avanafil 200 mg single-dose Cmax and AUC by approximately 2
Eintrag öffnenSpedra · 4.5 · CYP3A4 substrate Amlodipine (5 mg daily) increased avanafil 200 mg single-dose Cmax and AUC by approximately 2
Eintrag öffnenSpedra · 4.5 · Cytochrome P450 Inducers The potential effect of CYP inducers, especially inducers of CYP3A4 (e.g. bosentan, c
Eintrag öffnenSpedra · 4.5 · Cytochrome P450 Inducers The potential effect of CYP inducers, especially inducers of CYP3A4 (e.g. bosentan, c
Eintrag öffnenSpedra · 4.5 · Cytochrome P450 Inducers The potential effect of CYP inducers, especially inducers of CYP3A4 (e.g. bosentan, c
Eintrag öffnenSpedra · 4.5 · Cytochrome P450 Induction The potential induction of CYP1A2, CYP2B6 and CYP3A4 by avanafil evaluated in primar
Eintrag öffnenSpedra · 4.5 · Cytochrome P450 Induction The potential induction of CYP1A2, CYP2B6 and CYP3A4 by avanafil evaluated in primar
Eintrag öffnenSpedra · 4.5 · Cytochrome P450 Induction The potential induction of CYP1A2, CYP2B6 and CYP3A4 by avanafil evaluated in primar
Eintrag öffnenSpedra · 4.5 · Effects of avanafil on other medicinal products Cytochrome P450 Inhibition In in vitro studies in human liver
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