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Sprycel · 4.8 · Hepatitis B reactivation Hepatitis B reactivation has been reported in association with BCR-ABL TKIs. Some cas
Eintrag öffnenSprycel · 4.8 · In SPRYCEL-treated patients with newly diagnosed chronic phase CML who experienced grade 3 or 4 myelosuppressi
Eintrag öffnenSprycel · 4.8 · In SPRYCEL-treated patients with newly diagnosed chronic phase CML who experienced grade 3 or 4 myelosuppressi
Eintrag öffnenSprycel · 4.8 · In addition, there were two studies in a total of 161 paediatric patients with Ph+ ALL in which SPRYCEL was ad
Eintrag öffnenSprycel · 4.8 · In addition, there were two studies in a total of 161 paediatric patients with Ph+ ALL in which SPRYCEL was ad
Eintrag öffnenSprycel · 4.8 · In patients with CML with resistance or intolerance to prior imatinib therapy, cytopaenias (thrombocytopaenia,
Eintrag öffnenSprycel · 4.8 · In patients with CML with resistance or intolerance to prior imatinib therapy, cytopaenias (thrombocytopaenia,
Eintrag öffnenSprycel · 4.8 · In the 2,712 adult patients with either chronic phase CML, advanced phase CML or Ph+ ALL, the median duration
Eintrag öffnenSprycel · 4.8 · In the 2,712 adult patients with either chronic phase CML, advanced phase CML or Ph+ ALL, the median duration
Eintrag öffnenSprycel · 4.8 · In the Phase III dose-optimisation study in patients with advanced phase CML and Ph+ ALL, the median duration
Eintrag öffnenSprycel · 4.8 · In the Phase III dose-optimisation study in patients with advanced phase CML and Ph+ ALL, the median duration
Eintrag öffnenSprycel · 4.8 · In the Phase III dose-optimisation study in patients with chronic phase CML with resistance or intolerance to
Eintrag öffnenSprycel · 4.8 · In the Phase III dose-optimisation study in patients with chronic phase CML with resistance or intolerance to
Eintrag öffnenSprycel · 4.8 · In the paediatric ALL studies, the rates of laboratory abnormalities were consistent with the known profile fo
Eintrag öffnenSprycel · 4.8 · In the paediatric ALL studies, the rates of laboratory abnormalities were consistent with the known profile fo
Eintrag öffnenSprycel · 4.8 · In the paediatric CML studies, the rates of laboratory abnormalities were consistent with the known profile fo
Eintrag öffnenSprycel · 4.8 · In the paediatric CML studies, the rates of laboratory abnormalities were consistent with the known profile fo
Eintrag öffnenSprycel · 4.8 · Of the 126 Ph+ ALL paediatric patients on a continuous dosing regimen, 2 (1.6%) experienced adverse reactions
Eintrag öffnenSprycel · 4.8 · Of the 126 Ph+ ALL paediatric patients on a continuous dosing regimen, 2 (1.6%) experienced adverse reactions
Eintrag öffnenSprycel · 4.8 · Paediatric population The safety profile of SPRYCEL administered as single-agent therapy in paediatric patient
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