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Triumeq · 4.5 · In vitro, dolutegravir inhibited the renal transporters OCT2 and MATE1. In vivo, a 10-14% decrease of creatini
Eintrag öffnenTriumeq · 4.5 · In vitro, dolutegravir inhibited the renal uptake organic anion transporters (OAT)1 and OAT3. Based on the lac
Eintrag öffnenTriumeq · 4.5 · In vitro, dolutegravir inhibited the renal uptake organic anion transporters (OAT)1 and OAT3. Based on the lac
Eintrag öffnenTriumeq · 4.5 · In vitro, lamivudine was an inhibitor of OCT1 and OCT2; the clinical consequences are not known.
Eintrag öffnenTriumeq · 4.5 · In vitro, lamivudine was an inhibitor of OCT1 and OCT2; the clinical consequences are not known.
Eintrag öffnenTriumeq · 4.5 · In vivo, dolutegravir did not have an effect on midazolam, a CYP3A4 probe. Based on in vivo and/or in vitro da
Eintrag öffnenTriumeq · 4.5 · In vivo, dolutegravir did not have an effect on midazolam, a CYP3A4 probe. Based on in vivo and/or in vitro da
Eintrag öffnenTriumeq · 4.5 · Interaction studies have only been performed in adults.
Eintrag öffnenTriumeq · 4.5 · Interaction studies have only been performed in adults.
Eintrag öffnenTriumeq · 4.5 · Interaction table
Eintrag öffnenTriumeq · 4.5 · Interactions between dolutegravir, abacavir, lamivudine and co-administered medical products are listed in Tab
Eintrag öffnenTriumeq · 4.5 · Interactions between dolutegravir, abacavir, lamivudine and co-administered medical products are listed in Tab
Eintrag öffnenTriumeq · 4.5 · Lamivudine is cleared renally. Active renal secretion of lamivudine in the urine is mediated through the OCT2
Eintrag öffnenTriumeq · 4.5 · Lamivudine is cleared renally. Active renal secretion of lamivudine in the urine is mediated through the OCT2
Eintrag öffnenTriumeq · 4.5 · Lopinavir ↔ Ritonavir ↔
Eintrag öffnenTriumeq · 4.5 · Lopinavir ↔ Ritonavir ↔
Eintrag öffnenTriumeq · 4.5 · Lopinavir ↔ Ritonavir ↔ Etravirine ↔ Darunavir+ritonavir+etravirine/ Dolutegravir ↓ No dose adjustment is nece
Eintrag öffnenTriumeq · 4.5 · Lopinavir ↔ Ritonavir ↔ Etravirine ↔ Darunavir+ritonavir+etravirine/ Dolutegravir ↓ No dose adjustment is nece
Eintrag öffnenTriumeq · 4.5 · Lopinavir+ritonavir+etravirine/ Dolutegravir ↔ No dose adjustment is necessary. Dolutegravir AUC ↑ 11% Cmax ↑
Eintrag öffnenTriumeq · 4.5 · Lopinavir+ritonavir/ Abacavir Abacavir AUC ↓ 32% Darunavir+ritonavir/ Dolutegravir ↓ No dose adjustment is nec
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