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MicardisPlus · 4.3 · The concomitant use of telmisartan/HCTZ with aliskiren-containing products is contraindicated in patients with
Eintrag öffnenNeparvis · 4.5 · Aliskiren The concomitant use of sacubitril/valsartan with aliskiren-containing medicinal products is contrain
Eintrag öffnenNeparvis · 4.5 · Aliskiren The concomitant use of sacubitril/valsartan with aliskiren-containing medicinal products is contrain
Eintrag öffnenRasilez · 4.3 · - History of angioedema with aliskiren.
Eintrag öffnenRasilez · 4.3 · - The concomitant use of aliskiren with ciclosporin and itraconazole, two highly potent P-glycoprotein (P-gp)
Eintrag öffnenRasilez · 4.5 · 5 inhibiting organic anion transporting polypeptide-mediated uptake of aliskiren are widely present in fruits,
Eintrag öffnenRasilez · 4.5 · CYP450 interactions Aliskiren does not inhibit the CYP450 isoenzymes (CYP1A2, 2C8, 2C9, 2C19, 2D6, 2E1 and 3A)
Eintrag öffnenRasilez · 4.5 · Co-administration of aliskiren with either metformin (↓28%), amlodipine (↑29%) or cimetidine (↑19%) resulted i
Eintrag öffnenRasilez · 4.5 · Dual blockade of the RAAS with aliskiren, ARBs or ACEIs Clinical trial data has shown that dual blockade of th
Eintrag öffnenRasilez · 4.5 · Fruit juice and drinks containing plant extracts Administration of fruit juice with aliskiren resulted in a de
Eintrag öffnenRasilez · 4.5 · Furosemide and torasemide Oral co-administration of aliskiren and furosemide had no effect on the pharmacokine
Eintrag öffnenRasilez · 4.5 · In patients treated with both aliskiren and oral furosemide or torasemide, it is therefore recommended that th
Eintrag öffnenRasilez · 4.5 · Moderate P-gp inhibitors Co-administration of ketoconazole (200 mg) or verapamil (240 mg) with aliskiren (300
Eintrag öffnenRasilez · 4.5 · Non-steroidal anti-inflammatory drugs (NSAIDs) NSAIDs may reduce the anti-hypertensive effect of aliskiren. In
Eintrag öffnenRasilez · 4.5 · Organic anion transporting polypeptide (OATP) inhibitors Preclinical studies indicate that aliskiren might be
Eintrag öffnenRasilez · 4.5 · Warfarin The effects of aliskiren on warfarin pharmacokinetics have not been evaluated.
Eintrag öffnenRasilez · 4.8 · Aliskiren has been evaluated for safety in a randomised, double-blind, 8-week study in 267 hypertensive patien
Eintrag öffnenRasilez · 4.8 · Aliskiren has been evaluated for safety in more than 7,800 patients, including over 2,300 treated for over 6 m
Eintrag öffnenRasilez · 4.8 · Serum potassium Increases in serum potassium have been observed with aliskiren and these may be exacerbated by
Eintrag öffnenTelmisartan Actavis · 4.3 · The concomitant use of Telmisartan Actavis with aliskiren-containing products is contraindicated in patients w
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