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Deferasirox Mylan · 4.5 · Deferasirox metabolism depends on UGT enzymes. In a healthy volunteer study, the concomitant administration of
Eintrag öffnenDeferasirox Mylan · 4.5 · In a healthy volunteer study, the concomitant administration of deferasirox as a CYP1A2 inhibitor (repeated do
Eintrag öffnenDeferasirox Mylan · 4.5 · In a healthy volunteer study, the concomitant administration of deferasirox as a moderate CYP2C8 inhibitor (30
Eintrag öffnenDeferasirox Mylan · 4.5 · In a healthy volunteer study, the concomitant administration of deferasirox dispersible tablets and midazolam
Eintrag öffnenDeferasirox Mylan · 4.5 · Interaction with food
Eintrag öffnenDeferasirox Mylan · 4.5 · Interaction with midazolam and other agents metabolised by CYP3A4
Eintrag öffnenDeferasirox Mylan · 4.5 · Interaction with repaglinide and other agents metabolised by CYP2C8
Eintrag öffnenDeferasirox Mylan · 4.5 · Other information
Eintrag öffnenDeferasirox Mylan · 4.5 · The Cmax of deferasirox film-coated tablets was increased (by 29%) when taken with a high-fat meal. Deferasiro
Eintrag öffnenDeferasirox Mylan · 4.5 · The concomitant administration of deferasirox and aluminium-containing antacid preparations has not been forma
Eintrag öffnenDeferasirox Mylan · 4.5 · The concomitant administration of deferasirox with substances that have known ulcerogenic potential, such as N
Eintrag öffnenDeferasirox Mylan · 4.5 · The safety of deferasirox in combination with other iron chelators has not been established. Therefore, it mus
Eintrag öffnenDeferasirox Mylan · 4.6 Fertility, pregnancy and lactation · 1
Eintrag öffnenDeferasirox Mylan · 4.8 Undesirable effects · 1
Eintrag öffnenDeferasirox Mylan · 4.8 · 13 Gastrointestinal disorders Common: Diarrhoea, constipation, vomiting, nausea, abdominal pain, abdominal dis
Eintrag öffnenDeferasirox Mylan · 4.8 · 14 liver transaminases greater than 2 times the baseline and 5 times the upper limit of normal were reported i
Eintrag öffnenDeferasirox Mylan · 4.8 · Acute pancreatitis has been reported, particularly in children and adolescents.
Eintrag öffnenDeferasirox Mylan · 4.8 · Adverse reactions are ranked below using the following convention: very common (≥1/10); common (≥1/100 to <1/1
Eintrag öffnenDeferasirox Mylan · 4.8 · Blood and lymphatic system disorders Not known: Pancytopenia1, thrombocytopenia1, anaemia aggravated1, neutrop
Eintrag öffnenDeferasirox Mylan · 4.8 · Clinical study in patients with non-transfusion-dependent thalassaemia syndromes
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