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Ivabradine Anpharm · 4.5 · Moderate CYP3A4 inhibitors Specific interaction studies in healthy volunteers and patients have shown that the
Eintrag öffnenIvabradine Anpharm · 4.5 · Moderate CYP3A4 inhibitors The concomitant use of ivabradine with other moderate CYP3A4 inhibitors (e.g. fluco
Eintrag öffnenIvabradine Anpharm · 4.5 · Other concomitant use Specific interaction studies have shown no clinically significant effect of the followin
Eintrag öffnenIvabradine Anpharm · 4.5 · Paediatric population
Eintrag öffnenIvabradine Anpharm · 4.5 · Pharmacodynamic interactions
Eintrag öffnenIvabradine Anpharm · 4.5 · Pharmacokinetic interactions
Eintrag öffnenIvabradine Anpharm · 4.5 · Potassium-depleting diuretics (thiazide diuretics and loop diuretics) Hypokalemia can increase the risk of arr
Eintrag öffnenIvabradine Anpharm · 4.5 · Potent CYP3A4 inhibitors The concomitant use of potent CYP3A4 inhibitors such as azole antifungals (ketoconazo
Eintrag öffnenIvabradine Anpharm · 4.5 · QT prolonging medicinal products - Cardiovascular QT prolonging medicinal products (e.g. quinidine, disopyrami
Eintrag öffnenIvabradine Anpharm · 4.6 Fertility, pregnancy and lactation · 1
Eintrag öffnenIvabradine Anpharm · 4.8 Undesirable effects · 1
Eintrag öffnenIvabradine Anpharm · 4.8 · 8 Classified as confidential by the European Medicines Agency Tabulated list of adverse reactions
Eintrag öffnenIvabradine Anpharm · 4.8 · 9 Classified as confidential by the European Medicines Agency Description of selected adverse reactions
Eintrag öffnenIvabradine Anpharm · 4.8 · Bradycardia was reported by 3.3% of patients particularly within the first 2 to 3 months of treatment initiati
Eintrag öffnenIvabradine Anpharm · 4.8 · In the SHIFT trial more patients experienced episodes of increased blood pressure while treated with ivabradin
Eintrag öffnenIvabradine Anpharm · 4.8 · In the SIGNIFY study atrial fibrillation was observed in 5.3% of patients taking ivabradine compared to 3.8% i
Eintrag öffnenIvabradine Anpharm · 4.8 · Luminous phenomena (phosphenes) were reported by 14.5% of patients, described as a transient enhanced brightne
Eintrag öffnenIvabradine Anpharm · 4.8 · Reporting of suspected adverse reactions
Eintrag öffnenIvabradine Anpharm · 4.8 · Reporting suspected adverse reactions after authorisation of the medicinal product is important. It allows con
Eintrag öffnenIvabradine Anpharm · 4.8 · Summary of the safety profile
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