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20 angezeigte Treffer · Seite 4, keine Gesamtzahl für „sunitinib“
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Sunitinib Accord · 4.8 · Musculoskeletal Pain in extremity Musculoskeletal pain Osteonecrosis of the Rhabdomyolysis* and connective Art
Eintrag öffnenSunitinib Accord · 4.8 · Musculoskeletal and connective tissue disorders Cases of myopathy and/or rhabdomyolysis, some with acute renal
Eintrag öffnenSunitinib Accord · 4.8 · Nervous system Dizziness Neuropathy peripheral Cerebral Posterior reversible Hyperammon disorders Headache Par
Eintrag öffnenSunitinib Accord · 4.8 · No cases with fatal outcome were reported in GIST, MRCC, and pNET registrational studies. Cases with fatal out
Eintrag öffnenSunitinib Accord · 4.8 · Paediatric population The safety profile of sunitinib has been derived from a Phase 1 dose-escalation study, a
Eintrag öffnenSunitinib Accord · 4.8 · Patients who presented with pulmonary embolism within the previous 12 months were excluded from sunitinib clin
Eintrag öffnenSunitinib Accord · 4.8 · QTc interval prolongation was investigated in a trial in 24 patients, ages 20-87 years, with advanced malignan
Eintrag öffnenSunitinib Accord · 4.8 · Reporting of suspected adverse reactions Reporting suspected adverse reactions after authorisation of the medi
Eintrag öffnenSunitinib Accord · 4.8 · Seven patients (3%) on sunitinib and none on placebo in a Phase 3 GIST study experienced venous thromboembolic
Eintrag öffnenSunitinib Accord · 4.8 · Skin and subcutaneous tissue disorders Cases of pyoderma gangrenosum, generally reversible after discontinuati
Eintrag öffnenSunitinib Accord · 4.8 · Summary of the safety profile The most serious adverse reactions associated with sunitinib, some fatal, are re
Eintrag öffnenSunitinib Accord · 4.8 · Table 1. Adverse reactions reported in clinical studies System organ class Very common Common Uncommon Rare No
Eintrag öffnenSunitinib Accord · 4.8 · Tabulated list of adverse reactions Adverse reactions that were reported in GIST, MRCC, and pNET patients in a
Eintrag öffnenSunitinib Accord · 4.8 · Thirteen patients (3%) receiving sunitinib in the Phase 3 treatment-naïve MRCC study and 4 patients (2%) on th
Eintrag öffnenSunitinib Accord · 4.8 · Thyroid function was monitored prospectively in 2 studies in patients with breast cancer; sunitinib is not app
Eintrag öffnenSunitinib Accord · 4.8 · Using comprehensive serial ECG assessments at times corresponding to either therapeutic or greater than therap
Eintrag öffnenSunitinib Accord · 4.8 · Vascular disorders Hypertension Hypertension was a very common adverse reaction reported in clinicalstudies. T
Eintrag öffnenSunitinib Accord · 4.8 · Venous thromboembolic events Treatment-related venous thromboembolic events were reported in approximately 1.0
Eintrag öffnenSutent · 4.5 · 8 Medicinal products that may increase sunitinib plasma concentrations Effect of CYP3A4 inhibitors In healthy
Eintrag öffnenSutent · 4.5 · Administration of sunitinib with potent CYP3A4 inducers (e.g., dexamethasone, phenytoin, carbamazepine, rifamp
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