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Riximyo · 4.8 · In the post marketing setting, serious viral infections have been reported in RA patients treated with rituxim
Eintrag öffnenRiximyo · 4.8 · Infections In GPA/MPA Study 1, the overall rate of infection was approximately 237 per 100 patient years (95%
Eintrag öffnenRiximyo · 4.8 · Infections In PV Study 1, 14 patients (37%) in the rituximab group experienced treatment-related infections co
Eintrag öffnenRiximyo · 4.8 · Infections Rituximab induces B-cell depletion in about 70-80% of patients, but was associated with decreased s
Eintrag öffnenRiximyo · 4.8 · Infections The overall rate of infection reported from clinical trials was approximately 94 per 100 patient ye
Eintrag öffnenRiximyo · 4.8 · Infectious events (predominantly bacterial and viral) occurred in approximately 30-55% of patients during clin
Eintrag öffnenRiximyo · 4.8 · Infusion-related reactions In GPA/MPA Study 1 (adult induction of remission study), IRRs were defined as any a
Eintrag öffnenRiximyo · 4.8 · Infusion-related reactions In PV Study 1, infusion-related reactions were common (58%). Nearly all infusion-re
Eintrag öffnenRiximyo · 4.8 · Infusion-related reactions The most frequent adverse reactions following receipt of rituximab in clinical stud
Eintrag öffnenRiximyo · 4.8 · Laboratory abnormalities Hypogammaglobulinaemia (IgG or IgM below the lower limit of normal) has been observed
Eintrag öffnenRiximyo · 4.8 · Laboratory abnormalities In PV Study 2, in the rituximab arm, transient decreases in lymphocyte count, driven
Eintrag öffnenRiximyo · 4.8 · Localised candida infections as well as Herpes zoster were reported at a higher incidence in the rituximab-con
Eintrag öffnenRiximyo · 4.8 · Malignancies In GPA/MPA Study 1, the incidence of malignancy in rituximab treated patients in the GPA and MPA
Eintrag öffnenRiximyo · 4.8 · MedDRA Not known System organ Very common Common Uncommon Rare Very rare class Infections and Upper Bronchitis
Eintrag öffnenRiximyo · 4.8 · MedDRA Not known Very common Common System Organ Class Infections and infestations Upper respiratory Herpes vi
Eintrag öffnenRiximyo · 4.8 · MedDRA Not known Very common Common System organ class Infections and bronchitis rhinitis serious viral infect
Eintrag öffnenRiximyo · 4.8 · MedDRA Not known Very common Common System organ class Infections and urinary tract infection, serious viral i
Eintrag öffnenRiximyo · 4.8 · MedDRA Very System organ Common Uncommon Rare Very rare Not known common class Infections and Bacterial Sepsis
Eintrag öffnenRiximyo · 4.8 · Multiple courses Multiple courses of treatment are associated with a similar adverse reaction profile to that
Eintrag öffnenRiximyo · 4.8 · Neurologic disorders During the treatment period (induction treatment phase comprising of R-CHOP for at most e
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