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Simponi · 4.8 · 13 Liver enzyme elevations In the controlled period of RA and PsA pivotal trials, mild ALT elevations (> 1 and
Eintrag öffnenSimponi · 4.8 · 130 increase the risk of injection site reactions. The majority of the injection site reactions were mild and
Eintrag öffnenSimponi · 4.8 · 14 Ulcerative colitis The safety of golimumab has been studied in a Phase III study of 69 patients from 4 to 1
Eintrag öffnenSimponi · 4.8 · 37 Rare: Tuberculosis, opportunistic infections (such as invasive fungal infections [histoplasmosis, coccidioi
Eintrag öffnenSimponi · 4.8 · 38 Skin and subcutaneous tissue disorders Common: Pruritus, rash, alopecia, dermatitis Uncommon: Bullous skin
Eintrag öffnenSimponi · 4.8 · 39 3 years, there was a greater incidence of serious infections, including opportunistic infections and TB in
Eintrag öffnenSimponi · 4.8 · 40 Liver enzyme elevations In the controlled period of RA and PsA pivotal trials, mild ALT elevations (> 1 and
Eintrag öffnenSimponi · 4.8 · 41 Ulcerative colitis The safety of golimumab has been studied in a Phase III study of 69 patients from 4 to 1
Eintrag öffnenSimponi · 4.8 · 68 Endocrine disorders Uncommon: Thyroid disorder (such as hypothyroidism, hyperthyroidism and goitre) Metabol
Eintrag öffnenSimponi · 4.8 · 69 Rare: Impaired healing Injury, poisoning and procedural complications Common: Bone fractures * Observed wit
Eintrag öffnenSimponi · 4.8 · 70 Malignancies other than lymphoma In the controlled periods of pivotal trials and through approximately 4 ye
Eintrag öffnenSimponi · 4.8 · 71 similar in both golimumab-treated and control patients. In general these elevations were asymptomatic and t
Eintrag öffnenSimponi · 4.8 · 98 Blood and lymphatic system disorders Common: Leukopenia (including neutropenia), anaemia Uncommon: Thromboc
Eintrag öffnenSimponi · 4.8 · 99 Renal and urinary disorders Rare: Bladder disorders, renal disorders Reproductive system and breast disorde
Eintrag öffnenSimponi · 4.8 · Autoimmune antibodies In the controlled and uncontrolled periods of pivotal trials through 1 year of follow-up
Eintrag öffnenSimponi · 4.8 · Autoimmune antibodies In the controlled and uncontrolled periods of pivotal trials through 1 year of follow-up
Eintrag öffnenSimponi · 4.8 · Autoimmune antibodies In the controlled and uncontrolled periods of pivotal trials through 1 year of follow-up
Eintrag öffnenSimponi · 4.8 · Autoimmune antibodies In the controlled and uncontrolled periods of pivotal trials through 1 year of follow-up
Eintrag öffnenSimponi · 4.8 · Autoimmune antibodies In the controlled and uncontrolled periods of pivotal trials through 1 year of follow-up
Eintrag öffnenSimponi · 4.8 · Cases reported in clinical studies in asthma In an exploratory clinical study, patients with severe persistent
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