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Ogivri · 4.5 · No interaction studies have been performed. Clinically significant interactions between trastuzumab and the co
Eintrag öffnenOgivri · 4.5 · The administration of concomitant anastrozole did not appear to influence the pharmacokinetics of trastuzumab.
Eintrag öffnenOgivri · 4.8 · 14 reduced ventricular ejection fraction, have been observed in patients treated with trastuzumab (see section
Eintrag öffnenOgivri · 4.8 · 15 Pulmonary events Severe pulmonary adverse reactions occur in association with the use of trastuzumab and ha
Eintrag öffnenOgivri · 4.8 · Amongst the most serious and/or common adverse reactions reported in trastuzumab usage (intravenous and subcut
Eintrag öffnenOgivri · 4.8 · In 3 pivotal clinical trials of adjuvant trastuzumab given in combination with chemotherapy, the incidence of
Eintrag öffnenOgivri · 4.8 · In the pivotal metastatic trials of intravenous trastuzumab, the incidence of cardiac dysfunction varied betwe
Eintrag öffnenOgivri · 4.8 · Study MO22982 investigated switching between the trastuzumab intravenous and trastuzumab subcutaneous formulat
Eintrag öffnenOgivri · 4.8 · Switching treatment between trastuzumab intravenous and trastuzumab subcutaneous formulation and vice versa.
Eintrag öffnenOgivri · 4.8 · Table 1 Undesirable effects reported with intravenous trastuzumab monotherapy or in combination with chemother
Eintrag öffnenOgivri · 4.8 · The clinical relevance of these antibodies is not known. The presence of anti-trastuzumab antibodies had no im
Eintrag öffnenOgivri · 4.8 · There are no immunogenicity data available for trastuzumab in gastric cancer.
Eintrag öffnenOgivri · 4.8 · When trastuzumab was administered after completion of adjuvant chemotherapy NYHA Class III - IV heart failure
Eintrag öffnenOntruzant · 4.3 · • Hypersensitivity to trastuzumab, murine proteins, or to any of the excipients listed in section 6.1 • Severe
Eintrag öffnenOntruzant · 4.5 · By comparison of simulated serum trastuzumab concentrations after trastuzumab monotherapy (4 mg/kg loading/2 m
Eintrag öffnenOntruzant · 4.5 · Data from study JP16003, a single-arm study of trastuzumab (4 mg/kg loading dose as an intravenous infusion an
Eintrag öffnenOntruzant · 4.5 · Effect of antineoplastic agents on trastuzumab pharmacokinetics
Eintrag öffnenOntruzant · 4.5 · Effect of trastuzumab on the pharmacokinetics of other antineoplastic agents
Eintrag öffnenOntruzant · 4.5 · The administration of concomitant anastrozole did not appear to influence the pharmacokinetics of trastuzumab.
Eintrag öffnenOntruzant · 4.8 · In 3 pivotal clinical trials of adjuvant trastuzumab given in combination with chemotherapy, the incidence of
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