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Jakavi · 4.8 · In phase 3 studies in MF, high lipase values were reported in 18.7% and 19.3% of patients in the ruxolitinib a
Eintrag öffnenJakavi · 4.8 · In the clinical study programme the severity of adverse drug reactions was assessed based on the CTCAE, defini
Eintrag öffnenJakavi · 4.8 · In the clinical study programme the severity of adverse drug reactions was assessed based on the CTCAE, defini
Eintrag öffnenJakavi · 4.8 · In the comparative period of the phase 3 acute GvHD study (REACH2), bleeding events were reported in 25.0% and
Eintrag öffnenJakavi · 4.8 · In the comparative period of the phase 3 acute GvHD study (REACH2), new or worsened lipase values were reporte
Eintrag öffnenJakavi · 4.8 · In the comparative period of the phase 3 chronic GvHD study (REACH3), bleeding events were reported in 11.5% a
Eintrag öffnenJakavi · 4.8 · In the comparative period of the phase 3 chronic GvHD study (REACH3), bleeding events were reported in 11.5% a
Eintrag öffnenJakavi · 4.8 · In the comparative period of the phase 3 chronic GvHD study (REACH3), new or worsened lipase values were repor
Eintrag öffnenJakavi · 4.8 · In the comparative period of the phase 3 chronic GvHD study (REACH3), new or worsened lipase values were repor
Eintrag öffnenJakavi · 4.8 · In the phase 3 acute (REACH2) and chronic (REACH3) GvHD studies, anaemia (all grades) was reported in 75.0% an
Eintrag öffnenJakavi · 4.8 · In the phase 3 acute GvHD study (REACH2), during the comparative period, urinary tract infections were reporte
Eintrag öffnenJakavi · 4.8 · In the phase 3 acute GvHD study (REACH2), grade 3 and 4 neutropenia was observed in 17.9% and 20.6% of patient
Eintrag öffnenJakavi · 4.8 · In the phase 3 acute GvHD study (REACH2), grade 3 and 4 thrombocytopenia was observed in 31.3% and 47.7% of pa
Eintrag öffnenJakavi · 4.8 · In the phase 3 chronic GvHD study (REACH3), during the comparative period, urinary tract infections were repor
Eintrag öffnenJakavi · 4.8 · In the phase 3 chronic GvHD study (REACH3), during the comparative period, urinary tract infections were repor
Eintrag öffnenJakavi · 4.8 · In the randomised period of the phase 3 studies in PV patients, neutropenia was reported in 1.6% of patients e
Eintrag öffnenJakavi · 4.8 · In the randomised period of the phase 3 studies in PV patients, one (0.5%) CTCAE grade 3 and no grade 4 urinar
Eintrag öffnenJakavi · 4.8 · In the randomised period of the pivotal studies, anaemia was less frequent in PV patients than in MF patients
Eintrag öffnenJakavi · 4.8 · In the randomised period of the pivotal studies, the rate of patients experiencing thrombocytopenia was lower
Eintrag öffnenJakavi · 4.8 · In the randomised period of the pivotal study in PV patients, the mean systolic blood pressure increased by 0.
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