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Brukinsa · 4.5 · Co-administration with transport substrates/inhibitors
Eintrag öffnenBrukinsa · 4.5 · Co-administration with transport substrates/inhibitors
Eintrag öffnenBrukinsa · 4.5 · The coadministration of oral P-gp substrates with a narrow therapeutic index (e.g., digoxin) should be done wi
Eintrag öffnenCabometyx · 4.5 · MRP2 inhibitors In vitro data demonstrate that cabozantinib is a substrate of MRP2. Therefore, administration
Eintrag öffnenCabometyx · 4.5 · P-glycoprotein substrates Cabozantinib was an inhibitor (IC50 = 7.0 μM), but not a substrate, of Pgp transport
Eintrag öffnenCalquence · 4.5 · ACP-5862 may increase exposure to co-administered MATE1 substrates (e.g., metformin) by inhibition of MATE1 (s
Eintrag öffnenCalquence · 4.5 · ACP-5862 may increase exposure to co-administered MATE1 substrates (e.g., metformin) by inhibition of MATE1 (s
Eintrag öffnenCalquence · 4.5 · Acalabrutinib may increase exposure to co-administered BCRP substrates (e.g., methotrexate) by inhibition of i
Eintrag öffnenCalquence · 4.5 · Acalabrutinib may increase exposure to co-administered BCRP substrates (e.g., methotrexate) by inhibition of i
Eintrag öffnenCalquence · 4.5 · CYP3A substrates
Eintrag öffnenCalquence · 4.5 · CYP3A substrates
Eintrag öffnenCalquence · 4.5 · Effect of acalabrutinib on CYP1A2 substrates
Eintrag öffnenCalquence · 4.5 · Effect of acalabrutinib on CYP1A2 substrates
Eintrag öffnenCapecitabine Accord · 4.5 · Cytochrome P-450 2C9 substrates Other than warfarin, no formal interaction studies between capecitabine and ot
Eintrag öffnenCapecitabine Teva · 4.5 · Cytochrome P-450 2C9 substrates Other than warfarin, no formal interaction studies between capecitabine and ot
Eintrag öffnenCelsentri · 4.5 · Maraviroc is a substrate for the transporters P-glycoprotein and OATP1B1, but the effect of these transporters
Eintrag öffnenCelsentri · 4.5 · Maraviroc is a substrate for the transporters P-glycoprotein and OATP1B1, but the effect of these transporters
Eintrag öffnenCerdelga · 4.5 · CYP2D6 substrates After a single 50 mg dose of metoprolol, a CYP2D6 substrate, concomitant administration of r
Eintrag öffnenCerdelga · 4.5 · P-gp substrates After a single 0.25 mg dose of digoxin, a P-gp substrate, concomitant administration of 127 mg
Eintrag öffnenCholib · 4.5 · Interactions relevant to monotherapies Inhibitors of CYP 3A4 Simvastatin is a substrate of cytochrome P450 3A4
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