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Adcirca (previously Tadalafil Lilly) · 4.5 · Endothelin-1 receptor antagonists (e.g. bosentan) Bosentan (125 mg twice daily), a substrate of CYP2C9 and CYP
Eintrag öffnenAdcirca (previously Tadalafil Lilly) · 4.5 · Endothelin-1 receptor antagonists (e.g. bosentan) Bosentan (125 mg twice daily), a substrate of CYP2C9 and CYP
Eintrag öffnenAdcirca (previously Tadalafil Lilly) · 4.5 · In clinical pharmacology studies, the potential for tadalafil (10 and 20 mg) to augment the hypotensive effect
Eintrag öffnenAdcirca (previously Tadalafil Lilly) · 4.5 · In clinical pharmacology trials, the potential for tadalafil (10 and 20 mg) to augment the hypotensive effects
Eintrag öffnenAdcirca (previously Tadalafil Lilly) · 4.5 · In interaction studies performed in a limited number of healthy volunteers, these effects were not reported wi
Eintrag öffnenAdcirca (previously Tadalafil Lilly) · 4.5 · In interaction studies performed in a limited number of healthy volunteers, these effects were not reported wi
Eintrag öffnenAdcirca (previously Tadalafil Lilly) · 4.5 · Interaction studies have only been performed in adults.
Eintrag öffnenAdcirca (previously Tadalafil Lilly) · 4.5 · Interaction studies have only been performed in adults.
Eintrag öffnenAdcirca (previously Tadalafil Lilly) · 4.5 · Nitrates In clinical trials, tadalafil (5, 10 and 20 mg) was shown to augment the hypotensive effects of nitra
Eintrag öffnenAdcirca (previously Tadalafil Lilly) · 4.5 · Nitrates In clinical trials, tadalafil (5, 10 and 20 mg) was shown to augment the hypotensive effects of nitra
Eintrag öffnenAdcirca (previously Tadalafil Lilly) · 4.5 · Oral contraceptive At steady-state, tadalafil (40 mg once per day) increased ethinylestradiol exposure (AUC) b
Eintrag öffnenAdcirca (previously Tadalafil Lilly) · 4.5 · Oral contraceptive At steady-state, tadalafil (40 mg once per day) increased ethinylestradiol exposure (AUC) b
Eintrag öffnenAdcirca (previously Tadalafil Lilly) · 4.5 · P-glycoprotein substrates (e.g. digoxin) Tadalafil (40 mg once per day) had no clinically significant effect o
Eintrag öffnenAdcirca (previously Tadalafil Lilly) · 4.5 · Paediatric population
Eintrag öffnenAdcirca (previously Tadalafil Lilly) · 4.5 · Paediatric population
Eintrag öffnenAdcirca (previously Tadalafil Lilly) · 4.5 · Protease inhibitors (e.g. ritonavir) Ritonavir (200 mg twice daily), which is an inhibitor of CYP3A4, CYP2C9,
Eintrag öffnenAdcirca (previously Tadalafil Lilly) · 4.5 · Protease inhibitors (e.g. ritonavir) Ritonavir (200 mg twice daily), which is an inhibitor of CYP3A4, CYP2C9,
Eintrag öffnenAdcirca (previously Tadalafil Lilly) · 4.5 · Riociguat Preclinical studies showed an additive systemic blood pressure lowering effect when PDE5 inhibitors
Eintrag öffnenAdcirca (previously Tadalafil Lilly) · 4.5 · Riociguat Preclinical trials showed an additive systemic blood pressure lowering effect when PDE5 inhibitors w
Eintrag öffnenAdcirca (previously Tadalafil Lilly) · 4.5 · Terbutaline A similar increase in AUC and Cmax seen with ethinylestradiol may be expected with oral administra
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