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Begriffe & Kennungen
Ongentys · 4.5 · Opicapone is a weak in vitro inhibitor of CYP2C8 and OATP1B1, whereas repaglinide is a sensitive CYP2C8 and OA
Eintrag öffnenOrkambi · 4.5 · ↓ repaglinide A higher dose of repaglinide may be Due to induction of required to obtain the desired clinical
Eintrag öffnenOrkambi · 4.5 · ↓ repaglinide A higher dose of repaglinide may be required Due to induction of to obtain the desired clinical
Eintrag öffnenPlavix · 4.5 · CYP2C8 substrate medicinal products: Clopidogrel has been shown to increase repaglinide exposure in healthy vo
Eintrag öffnenPrandin · 4.3 · • Hypersensitivity to repaglinide or to any of the excipients listed in section 6.1. • Diabetes mellitus type
Eintrag öffnenPrandin · 4.3 · • Hypersensitivity to repaglinide or to any of the excipients listed in section 6.1. • Diabetes mellitus type
Eintrag öffnenPrandin · 4.3 · • Hypersensitivity to repaglinide or to any of the excipients listed in section 6.1. • Diabetes mellitus type
Eintrag öffnenPrandin · 4.5 · 14 repaglinide, may be altered by substances which influence these cytochrome P-450 enzymes via inhibition or
Eintrag öffnenPrandin · 4.5 · 15 dose of 0.25 mg) and ciclosporin (repeated dose at 100 mg) increased repaglinide AUC and Cmax about 2.5-fol
Eintrag öffnenPrandin · 4.5 · 24 can be increased if CYP2C8 is inhibited. Consequently metabolism, and by that clearance of repaglinide, may
Eintrag öffnenPrandin · 4.5 · 25 In a study conducted in healthy volunteers, the concomitant administration of repaglinide (a single dose of
Eintrag öffnenPrandin · 4.5 · 4 repaglinide, may be altered by substances which influence these cytochrome P-450 enzymes via inhibition or i
Eintrag öffnenPrandin · 4.5 · 5 dose of 0.25 mg) and ciclosporin (repeated dose at 100 mg) increased repaglinide AUC and Cmax about 2.5-fold
Eintrag öffnenPrandin · 4.5 · A number of medicinal products are known to influence repaglinide metabolism. Possible interactions should the
Eintrag öffnenPrandin · 4.5 · A number of medicinal products are known to influence repaglinide metabolism. Possible interactions should the
Eintrag öffnenPrandin · 4.5 · A number of medicinal products are known to influence repaglinide metabolism. Possible interactions should the
Eintrag öffnenPrandin · 4.5 · Based on in vitro data, repaglinide appears to be a substrate for active hepatic uptake (organic anion transpo
Eintrag öffnenPrandin · 4.5 · Based on in vitro data, repaglinide appears to be a substrate for active hepatic uptake (organic anion transpo
Eintrag öffnenPrandin · 4.5 · Based on in vitro data, repaglinide appears to be a substrate for active hepatic uptake (organic anion transpo
Eintrag öffnenPrandin · 4.5 · Co-administration of cimetidine, nifedipine, oestrogen, or simvastatin with repaglinide, all CYP3A4 substrates
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