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Etcamah · 4.5 · CYP3A4/5 substrates In a clinical study, concomitant use of camizestrant increased midazolam, a sensitive CYP3
Eintrag öffnenEtcamah · 4.5 · OATP1B1 sensitive substrates In vitro data show that camizestrant is an inhibitor of OATP1B1. Therefore, camiz
Eintrag öffnenEtcamah · 4.5 · P-gp sensitive substrates In vitro data show that camizestrant is an inhibitor of P-glycoprotein (P-gp). There
Eintrag öffnenEtcamah · 4.5 · The co-administration of camizestrant and moderately sensitive substrates of CYP2C9 (including but not limited
Eintrag öffnenEurartesim · 4.5 · Piperaquine has the potential to increase the rate of metabolism for CYP2E1 substrates resulting in a decrease
Eintrag öffnenEurartesim · 4.5 · Piperaquine has the potential to increase the rate of metabolism for CYP2E1 substrates resulting in a decrease
Eintrag öffnenEviplera · 4.5 · P-glycoprotein substrates Rilpivirine inhibits P-glycoprotein (P-gp) in vitro (IC50 is 9.2 µM). In a clinical
Eintrag öffnenEvrenzo · 4.5 · OATP1B1 or BCRP substrates Roxadustat is an inhibitor of BCRP and OATP1B1. These transporters play an importan
Eintrag öffnenEvrenzo · 4.5 · Roxadustat may increase the plasma exposure of other medicinal products that are substrates of BCRP or OATP1B1
Eintrag öffnenFebuxostat Viatris (previously Febuxostat Mylan) · 4.5 · Desipramine/CYP2D6 substrates
Eintrag öffnenFebuxostat Viatris (previously Febuxostat Mylan) · 4.5 · Desipramine/CYP2D6 substrates
Eintrag öffnenFebuxostat Viatris (previously Febuxostat Mylan) · 4.5 · Rosiglitazone/CYP2C8 substrates
Eintrag öffnenFebuxostat Viatris (previously Febuxostat Mylan) · 4.5 · Rosiglitazone/CYP2C8 substrates
Eintrag öffnenFebuxostat Viatris (previously Febuxostat Mylan) · 4.5 · Thus, co-administration of febuxostat with other CYP2D6 substrates is not expected to require any dose adjustm
Eintrag öffnenFingolimod Accord · 4.5 · Fingolimod is unlikely to interact with substances mainly cleared by the CYP450 enzymes or by substrates of th
Eintrag öffnenFintepla · 4.5 · Effect of fenfluramine on CYP2B6 and CYP3A4 substrates In vitro studies indicate that fenfluramine may induce
Eintrag öffnenFintepla · 4.5 · Effect of fenfluramine on CYP2D6 substrates In vitro studies indicate that fenfluramine may inhibit CYP2D6. It
Eintrag öffnenFintepla · 4.5 · Effect of fenfluramine on MATE1 substrates In vitro studies indicate that norfenfluramine (major and pharmacol
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Eintrag öffnenFycompa · 4.5 · Effect of perampanel on CYP3A substrates
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