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Besponsa · 4.8 · In the paediatric study (N=53), increases in QTcF of > 60 msec from baseline occurred in 7/49 (14%) patients,
Eintrag öffnenBesponsa · 4.8 · In the paediatric study (N=53), increases in amylases was reported in 1 (2%) patient as Grade 1.
Eintrag öffnenBesponsa · 4.8 · In the paediatric study (N=53), infusion-related reactions were reported in 23 (43%) patients. The most freque
Eintrag öffnenBesponsa · 4.8 · The most common (> 30%) adverse reactions in the paediatric study (N=53) were thrombocytopenia (51%), pyrexia
Eintrag öffnenBesponsa · 4.8 · The most common (≥ 2%) serious adverse reactions in the paediatric study were febrile neutropenia (15%), VOD (
Eintrag öffnenBetmiga · 4.8 · 33 parallel group, placebo-controlled sequential dose titration study. The most commonly reported adverse reac
Eintrag öffnenBetmiga · 4.8 · Adverse reactions observed during the 1-year (long term) active controlled (muscarinic antagonist) study were
Eintrag öffnenBetmiga · 4.8 · Adverse reactions observed during the 1-year (long term) active controlled (muscarinic antagonist) study were
Eintrag öffnenBeyonttra · 4.5 · Acoramidis is a substrate for BCRP. Based on an in vitro study, a clinically relevant interaction with BCRP in
Eintrag öffnenBeyonttra · 4.5 · Based on a clinical study in healthy adult volunteers, inhibition of organic anion transporter (OAT)-1 and -3
Eintrag öffnenBeyonttra · 4.5 · Based on an in vitro study, no drug-drug interaction with co-administered breast cancer resistance protein (BC
Eintrag öffnenBeyonttra · 4.5 · No dedicated in vivo drug-drug interaction study with gastric acid reducing agents was performed. Thus, the ef
Eintrag öffnenBeyonttra · 4.8 · Based on the clinical study, the most frequently reported adverse reactions were diarrhoea (11.6%) and gout (1
Eintrag öffnenBiktarvy · 4.8 · 15 Biktarvy was evaluated in a clinical study of 33 HIV-1 infected virologically suppressed (HIV-1 RNA < 50 co
Eintrag öffnenBiktarvy · 4.8 · Elderly Studies GS-US-380-1844, GS-US-380-1878 and the dedicated Study GS-US-380-4449 in patients ≥ 65 years o
Eintrag öffnenBlincyto · 4.8 · At a dose higher than the recommended dose in study MT103-205, a case of fatal cardiac failure occurred in the
Eintrag öffnenBlincyto · 4.8 · Capillary leak syndrome was observed in 1 patient in the phase II clinical study in adult patients with Philad
Eintrag öffnenBlincyto · 4.8 · In the randomised phase III clinical study (N = 267) and the single-arm phase II clinical study (N = 189) in p
Eintrag öffnenBlincyto · 4.8 · In the randomised phase III clinical study (N = 267) and the single-arm phase II clinical study (N = 189) in p
Eintrag öffnenBlincyto · 4.8 · In the randomised phase III clinical study (N = 267) and the single-arm phase II clinical study (N = 189) in p
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