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Aybintio
Eintrag öffnenAybintio · 4.1 Therapeutic indications · 1
Eintrag öffnenAybintio · 4.3 Contraindications · 1
Eintrag öffnenAybintio · 4.3 · • Hypersensitivity to the active substance or to any of the excipients listed in section 6.1. • Hypersensitivi
Eintrag öffnenAybintio · 4.4 Special warnings and precautions for use · 1
Eintrag öffnenAybintio · 4.5 Interaction with other medicinal products and other forms of interaction · 1
Eintrag öffnenAybintio · 4.5 · 9 bevacizumab plus chemotherapy, is associated with decreased progression-free survival (PFS) and/or overall s
Eintrag öffnenAybintio · 4.5 · Combination of bevacizumab and sunitinib malate In two clinical trials of metastatic renal cell carcinoma, mic
Eintrag öffnenAybintio · 4.5 · Combination with platinum- or taxane-based therapies (see sections 4.4 and 4.8) Increased rates of severe neut
Eintrag öffnenAybintio · 4.5 · EGFR monoclonal antibodies in combination with bevacizumab chemotherapy regimens No interaction studies have b
Eintrag öffnenAybintio · 4.5 · Effect of antineoplastic agents on bevacizumab pharmacokinetics No clinically relevant interaction of co-admin
Eintrag öffnenAybintio · 4.5 · Effect of bevacizumab on the pharmacokinetics of other antineoplastic agents No clinically relevant interactio
Eintrag öffnenAybintio · 4.5 · MAHA is a haemolytic disorder which can present with red cell fragmentation, anaemia, and thrombocytopenia. In
Eintrag öffnenAybintio · 4.5 · Radiotherapy The safety and efficacy of concomitant administration of radiotherapy and bevacizumab has not bee
Eintrag öffnenAybintio · 4.6 Fertility, pregnancy and lactation · 1
Eintrag öffnenAybintio · 4.8 Undesirable effects · 1
Eintrag öffnenAybintio · 4.8 · 10 Tabulated list of adverse reactions The adverse reactions listed in this section fall into the following fr
Eintrag öffnenAybintio · 4.8 · 11 System organ Uncommo Frequency not Very common Common Rare Very rare class n known Nervous system Periphera
Eintrag öffnenAybintio · 4.8 · 12 System organ Uncommo Frequency not Very common Common Rare Very rare class n known Reproductive Ovarian fai
Eintrag öffnenAybintio · 4.8 · 13 System organ Frequency not Very common Common Uncommon Rare Very rare class known Vascular disorders Hypert
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