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Capecitabine Medac
Eintrag öffnenCapecitabine Medac · 4.1 Therapeutic indications · 1
Eintrag öffnenCapecitabine Medac · 4.3 Contraindications · 1
Eintrag öffnenCapecitabine Medac · 4.3 · • History of severe and unexpected reactions to fluoropyrimidine therapy, • Hypersensitivity to the active sub
Eintrag öffnenCapecitabine Medac · 4.4 Special warnings and precautions for use · 1
Eintrag öffnenCapecitabine Medac · 4.5 Interaction with other medicinal products and other forms of interaction · 1
Eintrag öffnenCapecitabine Medac · 4.5 · 11 There was no clinically significant effect of bevacizumab on the pharmacokinetic parameters of capecitabine
Eintrag öffnenCapecitabine Medac · 4.5 · Allopurinol Interactions with allopurinol have been observed for 5-FU; with possible decreased efficacy of 5-F
Eintrag öffnenCapecitabine Medac · 4.5 · Antacid The effect of an aluminium hydroxide and magnesium hydroxide-containing antacid on the pharmacokinetic
Eintrag öffnenCapecitabine Medac · 4.5 · Bevacizumab
Eintrag öffnenCapecitabine Medac · 4.5 · Brivudine A clinically significant interaction between brivudine and fluoropyrimidines (e.g. capecitabine, 5-f
Eintrag öffnenCapecitabine Medac · 4.5 · Coumarin-derivative anticoagulants 10 Altered coagulation parameters and/or bleeding have been reported in pat
Eintrag öffnenCapecitabine Medac · 4.5 · Cytochrome P450 2C9 (CYP2C9) substrates Other than warfarin, no formal interaction studies between capecitabin
Eintrag öffnenCapecitabine Medac · 4.5 · Folinic acid/folic acid A combination study with capecitabine and folinic acid indicated that folinic acid has
Eintrag öffnenCapecitabine Medac · 4.5 · Food interaction In all clinical trials, patients were instructed to administer capecitabine within 30 minutes
Eintrag öffnenCapecitabine Medac · 4.5 · In a clinical pharmacokinetic interaction study, after a single 20 mg dose of warfarin, capecitabine treatment
Eintrag öffnenCapecitabine Medac · 4.5 · Interaction studies have only been performed in adults.
Eintrag öffnenCapecitabine Medac · 4.5 · Interaction with other medicinal products
Eintrag öffnenCapecitabine Medac · 4.5 · Interferon alpha The MTD of capecitabine was 2,000 mg/m² per day when combined with interferon alpha- 2a (3 MI
Eintrag öffnenCapecitabine Medac · 4.5 · Oxaliplatin No clinically significant differences in exposure to capecitabine or its metabolites, free platinu
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