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Conbriza
Eintrag öffnenConbriza · 4.1 Therapeutic indications · 1
Eintrag öffnenConbriza · 4.3 Contraindications · 1
Eintrag öffnenConbriza · 4.3 · Active or past history of venous thromboembolic events, including deep vein thrombosis, pulmonary embolism, an
Eintrag öffnenConbriza · 4.3 · CONBRIZA is only indicated for use in postmenopausal women. Bazedoxifene must not be taken by women of child-b
Eintrag öffnenConbriza · 4.3 · Hypersensitivity to the active substance or to any of the excipients listed in section 6.1.
Eintrag öffnenConbriza · 4.3 · Patients with signs or symptoms of endometrial cancer; safety in this patient group has not been adequately st
Eintrag öffnenConbriza · 4.3 · Unexplained uterine bleeding.
Eintrag öffnenConbriza · 4.4 Special warnings and precautions for use · 1
Eintrag öffnenConbriza · 4.5 Interaction with other medicinal products and other forms of interaction · 1
Eintrag öffnenConbriza · 4.5 · Bazedoxifene undergoes little or no cytochrome P450 (CYP)-mediated metabolism. Bazedoxifene does not induce or
Eintrag öffnenConbriza · 4.5 · Bazedoxifene undergoes metabolism by uridine diphosphate glucuronosyltransferase (UGT) enzymes in the intestin
Eintrag öffnenConbriza · 4.5 · In a 30-day study, bazedoxifene increased hormone-binding globulin concentrations, including corticosteroid-bi
Eintrag öffnenConbriza · 4.5 · There were no significant pharmacokinetic interactions between bazedoxifene and the following medicinal produc
Eintrag öffnenConbriza · 4.6 Fertility, pregnancy and lactation · 1
Eintrag öffnenConbriza · 4.8 Undesirable effects · 1
Eintrag öffnenConbriza · 4.8 · # There have been post-marketing reports of ocular events other than retinal vein thrombosis. These reports in
Eintrag öffnenConbriza · 4.8 · *In the osteoporosis treatment trial in 7,492 evaluable subjects (mean age=66 years), the bazedoxifene-treated
Eintrag öffnenConbriza · 4.8 · 5 System organ Very Common Uncommon Frequency not class common known (cannot be estimated from available data)
Eintrag öffnenConbriza · 4.8 · Adverse reactions are categorised according to the following frequencies: very common ( 1/10); common ( 1/10
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