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Cyramza
Eintrag öffnenCyramza · 4.1 Therapeutic indications · 1
Eintrag öffnenCyramza · 4.3 Contraindications · 1
Eintrag öffnenCyramza · 4.3 · For patients with NSCLC, ramucirumab is contraindicated where there is tumour cavitation or tumour involvement
Eintrag öffnenCyramza · 4.3 · Hypersensitivity to the active substance or to any of the excipients listed in section 6.1.
Eintrag öffnenCyramza · 4.4 Special warnings and precautions for use · 1
Eintrag öffnenCyramza · 4.5 Interaction with other medicinal products and other forms of interaction · 1
Eintrag öffnenCyramza · 4.5 · No drug-drug interactions were observed between ramucirumab and paclitaxel. The pharmacokinetics of paclitaxel
Eintrag öffnenCyramza · 4.6 Fertility, pregnancy and lactation · 1
Eintrag öffnenCyramza · 4.8 Undesirable effects · 1
Eintrag öffnenCyramza · 4.8 · 12 Within each frequency grouping, ADRs are presented in order of decreasing seriousness.
Eintrag öffnenCyramza · 4.8 · 13 Table 7: ADRs reported in patients treated with ramucirumab in combination with chemotherapy or erlotinib i
Eintrag öffnenCyramza · 4.8 · 14 Clinically relevant reactions (including Grade ≥3) associated with antiangiogenic therapy observed in ramuc
Eintrag öffnenCyramza · 4.8 · 15 progressive widening of distal femoral growth plate. The impact of this finding on growth is not known. No
Eintrag öffnenCyramza · 4.8 · Adverse reactions from other sources
Eintrag öffnenCyramza · 4.8 · Colorectal cancer
Eintrag öffnenCyramza · 4.8 · In the RAISE study, in mCRC patients treated with ramucirumab plus FOLFIRI, the most frequent (≥ 1 %) ADR that
Eintrag öffnenCyramza · 4.8 · No new safety concerns were identified based on the limited number of paediatric patients treated with ramucir
Eintrag öffnenCyramza · 4.8 · Paediatric population
Eintrag öffnenCyramza · 4.8 · Ramucirumab in combination with FOLFIRI
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