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Clopidogrel/Acetylsalicylic acid Zentiva (previously DuoCover)
Eintrag öffnenClopidogrel/Acetylsalicylic acid Zentiva (previously DuoCover) · 4.1 Therapeutic indications · 1
Eintrag öffnenClopidogrel/Acetylsalicylic acid Zentiva (previously DuoCover) · 4.3 Contraindications · 1
Eintrag öffnenClopidogrel/Acetylsalicylic acid Zentiva (previously DuoCover) · 4.3 · 3 Active pathological bleeding such as peptic ulcer or intracranial haemorrhage.
Eintrag öffnenClopidogrel/Acetylsalicylic acid Zentiva (previously DuoCover) · 4.3 · Due to the presence of both components of the medicinal product, Clopidogrel/Acetylsalicylic acid Zentiva is c
Eintrag öffnenClopidogrel/Acetylsalicylic acid Zentiva (previously DuoCover) · 4.3 · In addition, due to the presence of ASA, its use is also contraindicated in: Hypersensitivity to non-steroid
Eintrag öffnenClopidogrel/Acetylsalicylic acid Zentiva (previously DuoCover) · 4.4 Special warnings and precautions for use · 1
Eintrag öffnenClopidogrel/Acetylsalicylic acid Zentiva (previously DuoCover) · 4.5 Interaction with other medicinal products and other forms of interaction · 1
Eintrag öffnenClopidogrel/Acetylsalicylic acid Zentiva (previously DuoCover) · 4.5 · 6 Other concomitant therapy with clopidogrel Since clopidogrel is metabolised to its active metabolite partly
Eintrag öffnenClopidogrel/Acetylsalicylic acid Zentiva (previously DuoCover) · 4.5 · 7 Caution is required because ASA may inhibit the effect of uricosuric agents through competitive elimination
Eintrag öffnenClopidogrel/Acetylsalicylic acid Zentiva (previously DuoCover) · 4.5 · Acetazolamide Caution is recommended when co-administering salicylates with acetazolamide as there is an incre
Eintrag öffnenClopidogrel/Acetylsalicylic acid Zentiva (previously DuoCover) · 4.5 · Alcohol Alcohol may increase the risk of gastrointestinal injury when taken with ASA. Patients should be couns
Eintrag öffnenClopidogrel/Acetylsalicylic acid Zentiva (previously DuoCover) · 4.5 · Apart from the specific medicinal product interaction information described above, interaction studies with Cl
Eintrag öffnenClopidogrel/Acetylsalicylic acid Zentiva (previously DuoCover) · 4.5 · As with other oral P2Y12 inhibitors, co-administration of opioid agonists has the potential to delay and reduc
Eintrag öffnenClopidogrel/Acetylsalicylic acid Zentiva (previously DuoCover) · 4.5 · CYP2C8 substrate medicinal products: Clopidogrel has been shown to increase repaglinide exposure in healthy vo
Eintrag öffnenClopidogrel/Acetylsalicylic acid Zentiva (previously DuoCover) · 4.5 · Data from the CAPRIE study indicate that phenytoin and tolbutamide which are metabolised by CYP2C9 can be safe
Eintrag öffnenClopidogrel/Acetylsalicylic acid Zentiva (previously DuoCover) · 4.5 · Experimental data suggest that ibuprofen may inhibit the effect of low dose aspirin on platelet aggregation wh
Eintrag öffnenClopidogrel/Acetylsalicylic acid Zentiva (previously DuoCover) · 4.5 · Glycoprotein IIb/IIIa inhibitors Clopidogrel/Acetylsalicylic acid Zentiva should be used with caution in patie
Eintrag öffnenClopidogrel/Acetylsalicylic acid Zentiva (previously DuoCover) · 4.5 · Heparin In a clinical study conducted in healthy subjects, clopidogrel did not necessitate modification of the
Eintrag öffnenClopidogrel/Acetylsalicylic acid Zentiva (previously DuoCover) · 4.5 · Inconsistent data on the clinical implications of this pharmacokinetic (PK)/pharmacodynamic (PD) interaction i
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