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Effentora
Eintrag öffnenEffentora · 4.1 Therapeutic indications · 1
Eintrag öffnenEffentora · 4.3 Contraindications · 1
Eintrag öffnenEffentora · 4.3 · • Hypersensitivity to the active substance or to any of the excipients listed in section 6.1. • Patients witho
Eintrag öffnenEffentora · 4.4 Special warnings and precautions for use · 1
Eintrag öffnenEffentora · 4.5 Interaction with other medicinal products and other forms of interaction · 1
Eintrag öffnenEffentora · 4.5 · 8 verapamil) may result in increased fentanyl plasma concentrations, potentially causing serious adverse drug
Eintrag öffnenEffentora · 4.5 · Agents that affect CYP3A4 activity Fentanyl is metabolised mainly via the human cytochrome P450 3A4 isoenzyme
Eintrag öffnenEffentora · 4.5 · Agents that can increase CNS depressant effects Co-administration of fentanyl with other central nervous syste
Eintrag öffnenEffentora · 4.5 · CYP3A4 inducers Co-administration with agents that induce 3A4 activity may reduce the efficacy of Effentora.
Eintrag öffnenEffentora · 4.5 · CYP3A4 inhibitors The concomitant use of Effentora with strong CYP3A4 inhibitors (e.g., ritonavir, ketoconazol
Eintrag öffnenEffentora · 4.5 · Partial opioid agonists/antagonists The concomitant use of partial opioid agonists/antagonists (e.g. buprenorp
Eintrag öffnenEffentora · 4.5 · Sedative medicines such as benzodiazepines or related drugs The concomitant use of opioids with sedative medic
Eintrag öffnenEffentora · 4.5 · Serotoninergic agents Co-administration of fentanyl with a serotoninergic agent, such as a Selective Serotonin
Eintrag öffnenEffentora · 4.5 · Sodium oxybate Concomitant use of medicinal products containing sodium oxybate and fentanyl is contraindicated
Eintrag öffnenEffentora · 4.6 Fertility, pregnancy and lactation · 1
Eintrag öffnenEffentora · 4.8 Undesirable effects · 1
Eintrag öffnenEffentora · 4.8 · 10 Very common Common Uncommon Rare Not known Psychiatric Depression Euphoric Drug disorders Anxiety mood depe
Eintrag öffnenEffentora · 4.8 · 11 Very common Common Uncommon Rare Not known Tooth disorder Hepatobiliary Biliary disorders dilatation Skin a
Eintrag öffnenEffentora · 4.8 · 12 Loss of consciousness and respiratory arrest have been observed in the context of overdose (see section 4.9
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