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Elrexfio
Eintrag öffnenElrexfio · 4.1 Therapeutic indications · 1
Eintrag öffnenElrexfio · 4.3 Contraindications · 1
Eintrag öffnenElrexfio · 4.3 · Hypersensitivity to the active substance or to any of the excipients listed in section 6.1.
Eintrag öffnenElrexfio · 4.4 Special warnings and precautions for use · 1
Eintrag öffnenElrexfio · 4.5 Interaction with other medicinal products and other forms of interaction · 1
Eintrag öffnenElrexfio · 4.5 · 10 The initial release of cytokines associated with the start of ELREXFIO may suppress cytochrome P450 (CYP) e
Eintrag öffnenElrexfio · 4.5 · No interaction studies have been performed with ELREXFIO.
Eintrag öffnenElrexfio · 4.6 Fertility, pregnancy and lactation · 1
Eintrag öffnenElrexfio · 4.8 Undesirable effects · 1
Eintrag öffnenElrexfio · 4.8 · 11 pyrexia (29.0%), rash (27.9%), arthralgia (26.8%), hypokalaemia (23.5%), nausea (21.9%), dry skin (21.9%) a
Eintrag öffnenElrexfio · 4.8 · 12 Table 6. Adverse reactions in multiple myeloma patients treated with ELREXFIO in MagnetisMM-3 at the recomm
Eintrag öffnenElrexfio · 4.8 · 13 Among patients who developed ICANS, 66.7% received corticosteroids, 33.3% received tocilizumab (or siltuxim
Eintrag öffnenElrexfio · 4.8 · Adverse reactions are listed according to the MedDRA system organ classification and by frequency. Frequency c
Eintrag öffnenElrexfio · 4.8 · Among patients who developed CRS, associated symptoms included fever (98.1%), hypotension (20.8%), and hypoxia
Eintrag öffnenElrexfio · 4.8 · Cytokine release syndrome (CRS) CRS occurred in 57.9% of patients who received ELREXFIO at the recommended dos
Eintrag öffnenElrexfio · 4.8 · Description of selected adverse reactions
Eintrag öffnenElrexfio · 4.8 · Immune effector cell-associated neurotoxicity syndrome (ICANS) ICANS occurred in 3.3% of patients following tr
Eintrag öffnenElrexfio · 4.8 · Reporting of suspected adverse reactions
Eintrag öffnenElrexfio · 4.8 · Reporting suspected adverse reactions after authorisation of the medicinal product is important. It allows con
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