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Entacapone Orion
Eintrag öffnenEntacapone Orion · 4.1 Therapeutic indications · 1
Eintrag öffnenEntacapone Orion · 4.3 Contraindications · 1
Eintrag öffnenEntacapone Orion · 4.3 · - Hypersensitivity to the active substance or to peanut or soya or to any of the excipients listed in section
Eintrag öffnenEntacapone Orion · 4.4 Special warnings and precautions for use · 1
Eintrag öffnenEntacapone Orion · 4.5 Interaction with other medicinal products and other forms of interaction · 1
Eintrag öffnenEntacapone Orion · 4.5 · 4 experience of the clinical use of entacapone with several medicinal products, including MAO-A inhibitors, tr
Eintrag öffnenEntacapone Orion · 4.5 · Due to its affinity to cytochrome P450 2C9 in vitro (see section 5.2), entacapone may potentially interfere wi
Eintrag öffnenEntacapone Orion · 4.5 · Entacapone binds to human albumin binding site II which also binds several other medicinal products, including
Eintrag öffnenEntacapone Orion · 4.5 · Entacapone may be used with selegiline (a selective MAO-B inhibitor), but the daily dose of selegiline should
Eintrag öffnenEntacapone Orion · 4.5 · Entacapone may form chelates with iron in the gastrointestinal tract. Entacapone and iron preparations should
Eintrag öffnenEntacapone Orion · 4.5 · In single-dose studies in healthy volunteers, no interactions were observed between entacapone and imipramine
Eintrag öffnenEntacapone Orion · 4.5 · No interaction of entacapone with carbidopa has been observed with the recommended treatment schedule. Pharmac
Eintrag öffnenEntacapone Orion · 4.6 Fertility, pregnancy and lactation · 1
Eintrag öffnenEntacapone Orion · 4.8 Undesirable effects · 1
Eintrag öffnenEntacapone Orion · 4.8 · 5 Usually the adverse reactions caused by entacapone are mild to moderate. In clinical studies the most common
Eintrag öffnenEntacapone Orion · 4.8 · 6 ** The incidence rates of myocardial infarction and other ischaemic heart disease events (0.43% and 1.54%, r
Eintrag öffnenEntacapone Orion · 4.8 · Description of selected adverse reactions Entacapone in association with levodopa has been associated with iso
Eintrag öffnenEntacapone Orion · 4.8 · Dyskinesias (27%), nausea (11%), diarrhoea (8%), abdominal pain (7%) and dry mouth (4.2%) were reported signif
Eintrag öffnenEntacapone Orion · 4.8 · Impulse control disorders: Pathological gambling, increased libido, hypersexuality, compulsive spending or buy
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