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Erivedge
Eintrag öffnenErivedge · 4.1 Therapeutic indication · 1
Eintrag öffnenErivedge · 4.3 Contraindications · 1
Eintrag öffnenErivedge · 4.3 · Hypersensitivity to the active substance or to any of the excipients listed in section 6.1. Women who are
Eintrag öffnenErivedge · 4.4 Special warnings and precautions for use · 1
Eintrag öffnenErivedge · 4.5 Interaction with other medicinal products and other forms of interaction · 1
Eintrag öffnenErivedge · 4.5 · Clinically significant PK interactions between vismodegib and CYP450 inhibitors are not expected. Results from
Eintrag öffnenErivedge · 4.5 · Clinically significant PK interactions between vismodegib and CYP450 substrates are not expected. In vitro, CY
Eintrag öffnenErivedge · 4.5 · Clinically significant PK interactions between vismodegib and P-gp inhibitors are not expected. Results from a
Eintrag öffnenErivedge · 4.5 · Clinically significant pharmacokinetic (PK) interactions between vismodegib and pH elevating agents are not ex
Eintrag öffnenErivedge · 4.5 · Contraceptive steroids Results of a drug-drug interaction study conducted in cancer patients demonstrated that
Eintrag öffnenErivedge · 4.5 · Effects of concomitant medicinal products on vismodegib
Eintrag öffnenErivedge · 4.5 · Effects of vismodegib on concomitant medicinal products
Eintrag öffnenErivedge · 4.5 · Effects on specific enzymes and transporters In vitro studies indicate that vismodegib has the potential to ac
Eintrag öffnenErivedge · 4.5 · In vitro, vismodegib is an inhibitor of OATP1B1. It cannot be excluded that vismodegib may increase the exposu
Eintrag öffnenErivedge · 4.5 · When vismodegib is administered with CYP inducers (rifampicin, carbamazepine, phenytoin, St. John´s wort), exp
Eintrag öffnenErivedge · 4.6 Fertility, pregnancy and lactation · 1
Eintrag öffnenErivedge · 4.8 Undesirable effects · 1
Eintrag öffnenErivedge · 4.8 · 8 Table 1 ADRs occurring in patients treated with Erivedge
Eintrag öffnenErivedge · 4.8 · 9 professionals are asked to report any suspected adverse reactions via the national reporting system listed i
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