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Evista
Eintrag öffnenEvista · 4.1 Therapeutic indications · 1
Eintrag öffnenEvista · 4.3 Contraindications · 1
Eintrag öffnenEvista · 4.3 · Active or past history of venous thromboembolic events (VTE), including deep vein thrombosis, pulmonary emboli
Eintrag öffnenEvista · 4.3 · Evista should not be used in patients with signs or symptoms of endometrial cancer as safety in this patient g
Eintrag öffnenEvista · 4.3 · Hepatic impairment including cholestasis.
Eintrag öffnenEvista · 4.3 · Hypersensitivity to the active substance or to any of the excipients listed in section 6.1.
Eintrag öffnenEvista · 4.3 · Must not be used in women with child bearing potential (see section 4.6).
Eintrag öffnenEvista · 4.3 · Severe renal impairment.
Eintrag öffnenEvista · 4.3 · Unexplained uterine bleeding.
Eintrag öffnenEvista · 4.4 Special warnings and precautions for use · 1
Eintrag öffnenEvista · 4.5 Interaction with other medicinal products and other forms of interaction · 1
Eintrag öffnenEvista · 4.5 · 4 Raloxifene modestly increases hormone-binding globulin concentrations, including sex steroid binding globuli
Eintrag öffnenEvista · 4.5 · Co-administration of raloxifene and warfarin does not alter the pharmacokinetics of either compound. However,
Eintrag öffnenEvista · 4.5 · Concomitant use of vaginal oestrogen preparations was allowed in the clinical trial programme, if necessary to
Eintrag öffnenEvista · 4.5 · Concurrent administration of either calcium carbonate or aluminium and magnesium-hydroxide containing antacids
Eintrag öffnenEvista · 4.5 · In vitro, raloxifene did not interact with the binding of warfarin, phenytoin, or tamoxifen.
Eintrag öffnenEvista · 4.5 · Peak concentrations of raloxifene are reduced with co-administration with ampicillin. However, since the overa
Eintrag öffnenEvista · 4.5 · Raloxifene does not affect the steady-state AUC of digoxin. The Cmax of digoxin increased by less than 5 %.
Eintrag öffnenEvista · 4.5 · Raloxifene has no effect on the pharmacokinetics of methylprednisolone given as a single dose.
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