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Gazyvaro
Eintrag öffnenGazyvaro · 4.1 Therapeutic indications · 1
Eintrag öffnenGazyvaro · 4.3 Contraindications · 1
Eintrag öffnenGazyvaro · 4.3 · Hypersensitivity to the active substance or to any of the excipients listed in section 6.1.
Eintrag öffnenGazyvaro · 4.4 Special warnings and precautions for use · 1
Eintrag öffnenGazyvaro · 4.5 Interaction with other medicinal products and other forms of interaction · 1
Eintrag öffnenGazyvaro · 4.5 · A risk for interactions with other concomitantly used medicinal products cannot be excluded.
Eintrag öffnenGazyvaro · 4.5 · Co-administration with Gazyvaro had no effect on the pharmacokinetics of bendamustine, FC, chlorambucil or the
Eintrag öffnenGazyvaro · 4.5 · No formal drug-drug interaction studies have been performed, although limited drug-drug interaction sub-studie
Eintrag öffnenGazyvaro · 4.5 · Obinutuzumab is not a substrate, inhibitor, or inducer of cytochrome P450 (CYP450), uridine diphosphate glucur
Eintrag öffnenGazyvaro · 4.5 · Pharmacokinetic interactions
Eintrag öffnenGazyvaro · 4.5 · The combination of obinutuzumab with chlorambucil, bendamustine, CHOP or CVP may increase the risk of neutrope
Eintrag öffnenGazyvaro · 4.5 · Vaccination with live virus vaccines is not recommended during treatment and until B-cell recovery because of
Eintrag öffnenGazyvaro · 4.6 Fertility, pregnancy and lactation · 1
Eintrag öffnenGazyvaro · 4.8 Undesirable effects · 1
Eintrag öffnenGazyvaro · 4.8 · * Chemotherapy: Chlorambucil in CLL; bendamustine, CHOP, CVP in iNHL including FL § observed also during maint
Eintrag öffnenGazyvaro · 4.8 · **Based on clinical trial exposures in FL and CLL
Eintrag öffnenGazyvaro · 4.8 · 18 Chronic lymphocytic leukaemia (CLL) and follicular lymphoma (FL)
Eintrag öffnenGazyvaro · 4.8 · 19 Tabulated list of adverse reactions
Eintrag öffnenGazyvaro · 4.8 · 20 System organ class All Grades Grades 3-5† Frequency Gazyvaro + chemotherapy* Gazyvaro + chemotherapy* (CLL,
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