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Grepid
Eintrag öffnenGrepid · 4.1 Therapeutic indications · 1
Eintrag öffnenGrepid · 4.3 Contraindications · 1
Eintrag öffnenGrepid · 4.3 · • Hypersensitivity to the active substance or to any of the excipients listed in section 2 or section 6.1. • S
Eintrag öffnenGrepid · 4.4 Special warnings and precautions for use · 1
Eintrag öffnenGrepid · 4.5 Interaction with other medicinal products and other forms of interaction · 1
Eintrag öffnenGrepid · 4.5 · 6 Heparin: in a clinical study conducted in healthy subjects, clopidogrel did not necessitate modification of
Eintrag öffnenGrepid · 4.5 · 7 The plasma concentrations of the active metabolite was 20 % reduced (loading dose) and 14 % reduced (mainten
Eintrag öffnenGrepid · 4.5 · A significantly reduced platelet inhibition has been shown in HIV patients treated with ritonavir-or cobicista
Eintrag öffnenGrepid · 4.5 · Acetylsalicylic acid (ASA): ASA did not modify the clopidogrel-mediated inhibition of ADP-induced platelet agg
Eintrag öffnenGrepid · 4.5 · Apart from the specific medicinal product interaction information described above, interaction studies with cl
Eintrag öffnenGrepid · 4.5 · As with other oral P2Y12 inhibitors, co-administration of opioid agonists has the potential to delay and reduc
Eintrag öffnenGrepid · 4.5 · Boosted anti-retroviral therapy (ART): HIV patients treated with boosted anti-retroviral therapies (ART) are a
Eintrag öffnenGrepid · 4.5 · CYP2C8 substrate medicinal products: Clopidogrel has been shown to increase repaglinide exposure in healthy vo
Eintrag öffnenGrepid · 4.5 · Data from the CAPRIE study indicate that phenytoin and tolbutamide which are metabolised by CYP2C9 can be safe
Eintrag öffnenGrepid · 4.5 · Glycoprotein IIb/IIIa inhibitors: clopidogrel should be used with caution in patients who receive concomitant
Eintrag öffnenGrepid · 4.5 · Inconsistent data on the clinical implications of this pharmacokinetic (PK)/pharmacodynamic (PD) interaction i
Eintrag öffnenGrepid · 4.5 · Inducers of CYP2C19 Since clopidogrel is metabolised to its active metabolite partly by CYP2C19, use of medici
Eintrag öffnenGrepid · 4.5 · Inhibitors of CYP2C19 Since clopidogrel is metabolised to its active metabolite partly by CYP2C19, use of medi
Eintrag öffnenGrepid · 4.5 · Less pronounced reductions of metabolite exposure has been observed with pantoprazole or lansoprazole.
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