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Imfinzi
Eintrag öffnenImfinzi · 4.1 Therapeutic indications · 1
Eintrag öffnenImfinzi · 4.3 Contraindications · 1
Eintrag öffnenImfinzi · 4.3 · Hypersensitivity to the active substance(s) or to any of the excipients listed in section 6.1.
Eintrag öffnenImfinzi · 4.4 Special warnings and precautions for use · 1
Eintrag öffnenImfinzi · 4.5 Interaction with other medicinal products and other forms of interaction · 1
Eintrag öffnenImfinzi · 4.5 · No formal pharmacokinetic (PK) drug-drug interaction studies have been conducted with durvalumab. Since the pr
Eintrag öffnenImfinzi · 4.5 · The use of systemic corticosteroids or immunosuppressants before starting durvalumab, except physiological dos
Eintrag öffnenImfinzi · 4.6 Fertility, pregnancy and lactation · 1
Eintrag öffnenImfinzi · 4.8 Undesirable effects · 1
Eintrag öffnenImfinzi · 4.8 · 15 The safety of IMFINZI in combination with chemotherapy is based on pooled data in 2 244 patients from 6 stu
Eintrag öffnenImfinzi · 4.8 · 16 The frequency of treatment discontinuation due to adverse reactions was 6.5%. The most common adverse react
Eintrag öffnenImfinzi · 4.8 · 18 IMFINZI as monotherapy IMFINZI in combination Platinum-based with chemotherapy chemotherapy + IMFINZI + ola
Eintrag öffnenImfinzi · 4.8 · 19 c including fatal outcome. d includes gingivitis, oral infection, periodontitis, pulpitis dental, tooth abs
Eintrag öffnenImfinzi · 4.8 · 20 Table 4. Adverse drug reactions in patients treated with IMFINZI in combination with tremelimumab IMFINZI i
Eintrag öffnenImfinzi · 4.8 · 21 IMFINZI in combination with IMFINZI in combination with tremelimumab 75 mg and platinum- tremelimumab 300 m
Eintrag öffnenImfinzi · 4.8 · 22 w Includes autoimmune hepatitis, hepatitis, hepatocellular injury, hepatotoxicity, hepatitis acute and immu
Eintrag öffnenImfinzi · 4.8 · 24 In the HCC pool (n=462), immune-mediated hepatitis occurred in 34 (7.4%) patients, including Grade 3 in 20
Eintrag öffnenImfinzi · 4.8 · 27 corticosteroid treatment (at least 40 mg prednisone or equivalent per day) and 1 patient also received myco
Eintrag öffnenImfinzi · 4.8 · Constipation, Nausea, Constipationh, Nauseah, Vomiting Vomitingh, Stomatitish y z Common Stomatitis , Colitis
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