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20 angezeigte Treffer · Seite 1, keine Gesamtzahl für „Ivacaftor“
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Begriffe & Kennungen
CPIC · CFTR and Ivacaftor
Eintrag öffnenKalydeco · 4.5 · 11 Medicinal products affected by ivacaftor
Eintrag öffnenKalydeco · 4.5 · Administration of ivacaftor may increase systemic exposure of medicinal products that are sensitive substrates
Eintrag öffnenKalydeco · 4.5 · Administration of ivacaftor may increase systemic exposure of medicinal products that are sensitive substrates
Eintrag öffnenKalydeco · 4.5 · Co-administration of ciprofloxacin with ivacaftor did not affect the exposure of ivacaftor. No dose adjustment
Eintrag öffnenKalydeco · 4.5 · Co-administration of ciprofloxacin with ivacaftor did not affect the exposure of ivacaftor. No dose adjustment
Eintrag öffnenKalydeco · 4.5 · Co-administration of ivacaftor with grapefruit juice, which contains one or more components that moderately in
Eintrag öffnenKalydeco · 4.5 · Co-administration of ivacaftor with grapefruit juice, which contains one or more components that moderately in
Eintrag öffnenKalydeco · 4.5 · Co-administration of ivacaftor with rifampicin, a strong CYP3A inducer, decreased ivacaftor exposure (AUC) by
Eintrag öffnenKalydeco · 4.5 · Co-administration of ivacaftor with rifampicin, a strong CYP3A inducer, decreased ivacaftor exposure (AUC) by
Eintrag öffnenKalydeco · 4.5 · Co-administration with fluconazole, a moderate inhibitor of CYP3A, increased ivacaftor exposure by 3-fold and
Eintrag öffnenKalydeco · 4.5 · In vitro studies showed that ivacaftor is not a substrate for OATP1B1 or OATP1B3. Ivacaftor and its metabolite
Eintrag öffnenKalydeco · 4.5 · In vitro studies showed that ivacaftor is not a substrate for OATP1B1 or OATP1B3. Ivacaftor and its metabolite
Eintrag öffnenKalydeco · 4.5 · Ivacaftor has been studied with an oestrogen/progesterone oral contraceptive and was found to have no signific
Eintrag öffnenKalydeco · 4.5 · Ivacaftor has been studied with an oestrogen/progesterone oral contraceptive and was found to have no signific
Eintrag öffnenKalydeco · 4.5 · Ivacaftor is a sensitive CYP3A substrate. Co-administration with ketoconazole, a strong CYP3A inhibitor, incre
Eintrag öffnenKalydeco · 4.5 · Ivacaftor is a sensitive CYP3A substrate. Co-administration with ketoconazole, a strong CYP3A inhibitor, incre
Eintrag öffnenKalydeco · 4.5 · Ivacaftor is a substrate of CYP3A4 and CYP3A5. It is a weak inhibitor of CYP3A and P-glycoprotein (P-gp) and a
Eintrag öffnenKalydeco · 4.5 · Ivacaftor is a substrate of CYP3A4 and CYP3A5. It is a weak inhibitor of CYP3A and P-glycoprotein (P-gp) and a
Eintrag öffnenKalydeco · 4.5 · Ivacaftor may inhibit CYP2C9. Therefore, monitoring of the international normalised ratio (INR) is recommended
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