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Eintrag öffnenIvemend · 4.1 Therapeutic indications · 1
Eintrag öffnenIvemend · 4.3 Contraindications · 1
Eintrag öffnenIvemend · 4.3 · Co-administration with pimozide, terfenadine, astemizole or cisapride (see section 4.5).
Eintrag öffnenIvemend · 4.3 · Hypersensitivity to the active substance or to polysorbate 80 or any of the other excipients listed in section
Eintrag öffnenIvemend · 4.4 Special warnings and precautions for use · 1
Eintrag öffnenIvemend · 4.5 Interaction with other medicinal products and other forms of interaction · 1
Eintrag öffnenIvemend · 4.5 · 5-HT3 antagonists Interaction studies with fosaprepitant 150 mg and 5-HT3 antagonists have not been conducted;
Eintrag öffnenIvemend · 4.5 · 7 Immunosuppressants Following a single 150 mg fosaprepitant dose, a transient moderate increase for two days
Eintrag öffnenIvemend · 4.5 · 8 Effect of other medicinal products on the pharmacokinetics of aprepitant resulting from administration of fo
Eintrag öffnenIvemend · 4.5 · Chemotherapeutic medicinal products Interaction studies with fosaprepitant 150 mg and chemotherapeutic medicin
Eintrag öffnenIvemend · 4.5 · Concomitant administration of fosaprepitant with active substances that strongly induce CYP3A4 activity (e.g.,
Eintrag öffnenIvemend · 4.5 · Corticosteroids Dexamethasone: The oral dexamethasone dose should be reduced by approximately 50 % when co-adm
Eintrag öffnenIvemend · 4.5 · Diltiazem Interaction studies with fosaprepitant 150 mg and diltiazem have not been conducted; however, the fo
Eintrag öffnenIvemend · 4.5 · Diltiazem Interaction studies with fosaprepitant 150 mg and diltiazem have not been conducted; however, the fo
Eintrag öffnenIvemend · 4.5 · Effect of fosaprepitant on the pharmacokinetics of other active substances CYP3A4 inhibition As a weak inhibit
Eintrag öffnenIvemend · 4.5 · Fosaprepitant 150 mg, given as a single dose, is a weak inhibitor of CYP3A4. Fosaprepitant does not seem to in
Eintrag öffnenIvemend · 4.5 · Hormonal contraceptives The efficacy of hormonal contraceptives may be reduced during and for 28 days after ad
Eintrag öffnenIvemend · 4.5 · Induction The fosaprepitant 150 mg single dose did not induce CYP3A4 on Days 1 and 4 in the midazolam interact
Eintrag öffnenIvemend · 4.5 · Interactions with other medicinal products following administration of intravenous fosaprepitant are likely to
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