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Jemperli
Eintrag öffnenJemperli · 4.1 Therapeutic indications · 1
Eintrag öffnenJemperli · 4.3 Contraindications · 1
Eintrag öffnenJemperli · 4.3 · Hypersensitivity to the active substance or to any of the excipients listed in section 6.1.
Eintrag öffnenJemperli · 4.4 Special warnings and precautions for use · 1
Eintrag öffnenJemperli · 4.5 Interaction with other medicinal products and other forms of interaction · 1
Eintrag öffnenJemperli · 4.5 · No interaction studies have been performed. Monoclonal antibodies (mAb) such as dostarlimab are not substrates
Eintrag öffnenJemperli · 4.6 Fertility, pregnancy and lactation · 1
Eintrag öffnenJemperli · 4.8 Undesirable effects · 1
Eintrag öffnenJemperli · 4.8 · 10 The safety profile for patients with dMMR/MSI-H EC in the GARNET study (N = 153) was not different from tha
Eintrag öffnenJemperli · 4.8 · 11 Dostarlimab monotherapy Dostarlimab in combination with chemotherapy Uncommon Type 1 diabetes mellitus, dia
Eintrag öffnenJemperli · 4.8 · 12 g Includes uveitis and iridocyclitis h Includes myocarditis and immune-mediated myocarditis i Includes pneu
Eintrag öffnenJemperli · 4.8 · 13 Adrenal insufficiency occurred in 7 (1.2 %) patients, including grade 2 (0.5 %), and grade 3 (0.7 %). Adren
Eintrag öffnenJemperli · 4.8 · 14 Reporting of suspected adverse reactions
Eintrag öffnenJemperli · 4.8 · Adverse reactions known to occur with dostarlimab as monotherapy, or with carboplatin or paclitaxel given alon
Eintrag öffnenJemperli · 4.8 · Adverse reactions reported in clinical trials of dostarlimab as a monotherapy or in combination with chemother
Eintrag öffnenJemperli · 4.8 · Description of selected adverse reactions
Eintrag öffnenJemperli · 4.8 · Dostarlimab in combination with carboplatin and paclitaxel
Eintrag öffnenJemperli · 4.8 · Dostarlimab in monotherapy
Eintrag öffnenJemperli · 4.8 · Dostarlimab is most commonly associated with immune-related adverse reactions. Most of these, including severe
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