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Jentadueto
Eintrag öffnenJentadueto · 4.1 Therapeutic indications · 1
Eintrag öffnenJentadueto · 4.3 Contraindications · 1
Eintrag öffnenJentadueto · 4.3 · • Hypersensitivity to the active substances or to any of the excipients listed in section 6.1. • Any type of a
Eintrag öffnenJentadueto · 4.4 Special warnings and precautions for use · 1
Eintrag öffnenJentadueto · 4.5 Interaction with other medicinal products and other forms of interaction · 1
Eintrag öffnenJentadueto · 4.5 · 6 respectively, and about 30% decreased DPP-4 inhibition at trough. Thus full efficacy of linagliptin in combi
Eintrag öffnenJentadueto · 4.5 · 7 Organic cation transporters (OCT) Metformin is a substrate of both transporters OCT1 and OCT2. Co-administra
Eintrag öffnenJentadueto · 4.5 · Caution is therefore advised, especially in patients with renal impairment, when these drugs are coadministere
Eintrag öffnenJentadueto · 4.5 · Concomitant use not recommended Alcohol Alcohol intoxication is associated with an increased risk of lactic ac
Eintrag öffnenJentadueto · 4.5 · Digoxin: Co-administration of multiple daily doses of 5 mg linagliptin with multiple doses of 0.25 mg digoxin
Eintrag öffnenJentadueto · 4.5 · Effects of linagliptin on other medicinal products In clinical studies, as described below, linagliptin had no
Eintrag öffnenJentadueto · 4.5 · In vivo assessment of interactions Effects of other medicinal products on linagliptin Clinical data described
Eintrag öffnenJentadueto · 4.5 · Iodinated contrast agents Jentadueto must be discontinued prior to or at the time of the imaging procedure and
Eintrag öffnenJentadueto · 4.5 · Linagliptin In vitro assessment of interactions Linagliptin is a weak competitive and a weak to moderate mecha
Eintrag öffnenJentadueto · 4.5 · Linagliptin is a P-glycoprotein substrate, and inhibits P-glycoprotein mediated transport of digoxin with low
Eintrag öffnenJentadueto · 4.5 · Metformin Combination requiring precautions for use Glucocorticoids (given by systemic and local routes), beta
Eintrag öffnenJentadueto · 4.5 · Metformin: Co-administration of multiple daily doses of 10 mg linagliptin with 850 mg metformin hydrochloride,
Eintrag öffnenJentadueto · 4.5 · Metformin: Co-administration of multiple three-times-daily doses of 850 mg metformin hydrochloride with 10 mg
Eintrag öffnenJentadueto · 4.5 · No interaction studies have been performed. However, such studies have been conducted with the individual acti
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