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Kerendia
Eintrag öffnenKerendia · 4.1 Therapeutic indications · 1
Eintrag öffnenKerendia · 4.3 Contraindications · 1
Eintrag öffnenKerendia · 4.3 · - Hypersensitivity to the active substance or to any of the excipients listed in section 6.1. - Concomitant tr
Eintrag öffnenKerendia · 4.4 Special warnings and precautions for use · 1
Eintrag öffnenKerendia · 4.5 Interaction with other medicinal products and other forms of interaction · 1
Eintrag öffnenKerendia · 4.5 · 9 Concomitant use with precautions
Eintrag öffnenKerendia · 4.5 · Antihypertensive medicinal products The risk for hypotension increases with concomitant use of multiple other
Eintrag öffnenKerendia · 4.5 · At 40 mg once daily, finerenone is a weak inhibitor of the CYP2C8 enzyme in vivo. Co-administration of multipl
Eintrag öffnenKerendia · 4.5 · Certain medicinal products that increase serum potassium (see section 4.4) Concomitant use of Kerendia with po
Eintrag öffnenKerendia · 4.5 · Certain medicinal products that increase serum potassium Kerendia should not be used concomitantly with potass
Eintrag öffnenKerendia · 4.5 · Concomitant use contraindicated
Eintrag öffnenKerendia · 4.5 · Concomitant use not recommended
Eintrag öffnenKerendia · 4.5 · Effect of 40 mg finerenone on CYP3A4 and CYP2C8 substrates At 40 mg once daily, finerenone is a weak inhibitor
Eintrag öffnenKerendia · 4.5 · Finerenone is cleared almost exclusively via cytochrome P450 (CYP)-mediated oxidative metabolism (mainly CYP3A
Eintrag öffnenKerendia · 4.5 · Grapefruit Grapefruit or grapefruit juice should not be consumed during finerenone treatment, as it is expecte
Eintrag öffnenKerendia · 4.5 · Interaction studies have only been performed in adults.
Eintrag öffnenKerendia · 4.5 · Moderate CYP3A4 inhibitors In a clinical study, concomitant use of erythromycin (500 mg three times a day) led
Eintrag öffnenKerendia · 4.5 · Strong CYP3A4 inhibitors Concomitant use of Kerendia with itraconazole, clarithromycin and other strong CYP3A4
Eintrag öffnenKerendia · 4.5 · Strong and moderate CYP3A4 inducers Kerendia should not be used concomitantly with rifampicin and other strong
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