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Kisqali
Eintrag öffnenKisqali · 4.1 Therapeutic indications · 1
Eintrag öffnenKisqali · 4.3 Contraindications · 1
Eintrag öffnenKisqali · 4.3 · Hypersensitivity to the active substance or to peanut, soya or any of the excipients listed in section 6.1.
Eintrag öffnenKisqali · 4.4 Special warnings and precautions for use · 1
Eintrag öffnenKisqali · 4.5 Interaction with other medicinal products and other forms of interaction · 1
Eintrag öffnenKisqali · 4.5 · 10 consulted for the recommendations regarding co-administration with CYP3A4 inhibitors. Caution is recommende
Eintrag öffnenKisqali · 4.5 · 11 Drug-drug interactions between ribociclib and oral contraceptives
Eintrag öffnenKisqali · 4.5 · 9 The concomitant use of strong CYP3A4 inhibitors including, but not limited to, the following must be avoided
Eintrag öffnenKisqali · 4.5 · Anti-arrhythmic medicinal products and other medicinal products that may prolong the QT interval Co-administra
Eintrag öffnenKisqali · 4.5 · Anticipated interactions
Eintrag öffnenKisqali · 4.5 · Co-administration of caffeine (CYP1A2 substrate) with multiple doses of Kisqali (400 mg) increased the caffein
Eintrag öffnenKisqali · 4.5 · Co-administration of midazolam (CYP3A4 substrate) with multiple doses of Kisqali (400 mg) increased the midazo
Eintrag öffnenKisqali · 4.5 · Co-administration of the strong CYP3A4 inducer rifampicin (600 mg daily for 14 days) with a single 600 mg dose
Eintrag öffnenKisqali · 4.5 · Concomitant administration of ribociclib with the following CYP3A4 substrates should be avoided: alfuzosin, am
Eintrag öffnenKisqali · 4.5 · Data from a clinical study in patients with breast cancer and population pharmacokinetic analysis indicated no
Eintrag öffnenKisqali · 4.5 · Data from a clinical study in patients with breast cancer indicated no clinically relevant drug interaction be
Eintrag öffnenKisqali · 4.5 · Data from a clinical study in patients with breast cancer indicated no clinically relevant effects of fulvestr
Eintrag öffnenKisqali · 4.5 · Data from a clinical study in patients with breast cancer indicated that tamoxifen exposure was increased appr
Eintrag öffnenKisqali · 4.5 · Drug-drug interaction between ribociclib and anastrozole
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